7ZFM
Engineered Protein Targeting the Zika Viral Envelope Fusion Loop
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Peptidyl-prolyl cis-trans isomerase A | polymer | 191 | 20675.0 | 2 | UniProt (P0AFL3) Pfam (PF00160) In PDB | Escherichia coli K-12 | PPIase A,Cyclophilin A,Rotamase A,ZVAP3 |
2 | B, A | 1,2-ETHANEDIOL | non-polymer | 62.1 | 17 | Chemie (EDO) | |||
3 | A | HEXAETHYLENE GLYCOL | non-polymer | 282.3 | 1 | Chemie (P6G) | |||
4 | A, B | TRIETHYLENE GLYCOL | non-polymer | 150.2 | 2 | Chemie (PGE) | |||
5 | A | ACETIC ACID | non-polymer | 60.1 | 3 | Chemie (ACY) | |||
6 | A, B | SUCCINIC ACID | non-polymer | 118.1 | 2 | Chemie (SIN) | |||
7 | water | water | 18.0 | 291 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 163 (UniProt: P0AFL3)
PDB | External Database | Details |
---|---|---|
Met -20 | - | initiating methionine |
Gly -19 | - | expression tag |
Ser -18 | - | expression tag |
Ser -17 | - | expression tag |
His -16 | - | expression tag |
His -15 | - | expression tag |
His -14 | - | expression tag |
His -13 | - | expression tag |
His -12 | - | expression tag |
His -11 | - | expression tag |
Ser -10 | - | expression tag |
Ser -9 | - | expression tag |
Gly -8 | - | expression tag |
Leu -7 | - | expression tag |
Val -6 | - | expression tag |
Pro -5 | - | expression tag |
Arg -4 | - | expression tag |
Gly -3 | - | expression tag |
Ser -2 | - | expression tag |
His -1 | - | expression tag |
Met 0 | - | expression tag |
Ser 22 | Lys 46 | engineered mutation |
Leu 33 | Val 57 | engineered mutation |
Asn 38 | Ser 62 | engineered mutation |
Ser 48 | Arg 72 | engineered mutation |
Tyr 53 | Phe 77 | engineered mutation |
Tyr 60 | Phe 84 | engineered mutation |
Asp 63 | Gln 87 | engineered mutation |
Gln 68 | Lys 92 | engineered mutation |
Met 91 | Ala 115 | engineered mutation |
Glu 94 | Ala 118 | engineered mutation |
Tyr 112 | Phe 136 | engineered mutation |
Ala 113 | Leu 137 | engineered mutation |
Thr 118 | Arg 142 | engineered mutation |
Arg 119 | Asp 143 | engineered mutation |
Tyr 120 | Phe 144 | engineered mutation |
Phe 122 | Tyr 146 | engineered mutation |
Ser 151 | Asn 175 | engineered mutation |
Thr 163 | Lys 187 | engineered mutation |
Val 164 | - | expression tag |
Leu 165 | - | expression tag |
Pro 166 | - | expression tag |
Gly 167 | - | expression tag |
Ser 168 | - | expression tag |
Gly 169 | - | expression tag |
Cys 170 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 41350.0 | |
Non-Polymers* | Number of molecules | 25 |
Total formula weight | 2054.2 | |
All* | Total formula weight | 43404.2 |