7ZFB
SARS-CoV-2 Omicron RBD in complex with nanobody C1, Omi-18 and Omi-31 Fabs
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | M, N | Nanobody C1 | polymer | 131 | 14659.1 | 2 | Lama glama (llama) | ||
2 | E, F | Spike protein S1 | polymer | 202 | 23157.2 | 2 | UniProt (P0DTC2) Pfam (PF09408) In PDB | Severe acute respiratory syndrome coronavirus 2 | SARS-CoV-2 Omicron Spike protein |
3 | A, C | Omi-31 heavy chain | polymer | 233 | 24802.9 | 2 | Homo sapiens (human) | ||
4 | B, D | Omi-31 light chain | polymer | 216 | 22780.1 | 2 | Homo sapiens (human) | ||
5 | H, J | Omi-18 heavy chain | polymer | 222 | 23376.3 | 2 | Homo sapiens (human) | ||
6 | L, K | Omi-18 light chain | polymer | 213 | 22833.0 | 2 | Homo sapiens (human) | ||
7 | E, F | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 2 | Chemie (NAG) |
Sequence modifications
E, F: 333 - 526 (UniProt: P0DTC2)
PDB | External Database | Details |
---|---|---|
His 327 | - | expression tag |
His 328 | - | expression tag |
His 329 | - | expression tag |
His 330 | - | expression tag |
His 331 | - | expression tag |
His 332 | - | expression tag |
Asp 339 | Gly 339 | variant |
Leu 371 | Ser 371 | variant |
Pro 373 | Ser 373 | variant |
Phe 375 | Ser 375 | variant |
Asn 417 | Lys 417 | variant |
Lys 440 | Asn 440 | variant |
Ser 446 | Gly 446 | variant |
Asn 477 | Ser 477 | variant |
Lys 478 | Thr 478 | variant |
Ala 484 | Glu 484 | variant |
Arg 493 | Gln 493 | variant |
Ser 496 | Gly 496 | variant |
Arg 498 | Gln 498 | conflict |
Tyr 501 | Asn 501 | variant |
His 505 | Tyr 505 | variant |
Lys 527 | - | expression tag |
Lys 528 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 12 |
Total formula weight | 263217.2 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 442.4 | |
All* | Total formula weight | 263659.6 |