7ZF7

SARS-CoV-2 Omicron BA.2 RBD in complex with ACE2

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Processed angiotensin-converting enzyme 2	polymer	604	70139.8	1	UniProt (Q9BYF1) Pfam (PF01401) In PDB	Homo sapiens (human)
2	B	Spike protein S1	polymer	209	23753.8	1	UniProt (P0DTC2) Pfam (PF09408) In PDB	Severe acute respiratory syndrome coronavirus 2	SARS-CoV-2 Omicron BA.2 Spike protein
3	A	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	6	Chemie (NAG)
4	A	ZINC ION	non-polymer		65.4	1	Chemie (ZN)

Sequence modifications

A: 19 - 615 (UniProt: Q9BYF1)

PDB	External Database	Details
Arg 616	-	expression tag
His 617	-	expression tag
His 618	-	expression tag
His 619	-	expression tag
His 620	-	expression tag
His 621	-	expression tag
His 622	-	expression tag

B: 330 - 532 (UniProt: P0DTC2)

PDB	External Database	Details
Asp 339	Gly 339	variant
Phe 371	Ser 371	variant
Pro 373	Ser 373	variant
Phe 375	Ser 375	variant
Ala 376	Thr 376	variant
Asn 405	Asp 405	variant
Ser 408	Arg 408	variant
Asn 417	Lys 417	variant
Lys 440	Asn 440	variant
Asn 477	Ser 477	variant
Lys 478	Thr 478	variant
Ala 484	Glu 484	variant
Arg 493	Gln 493	variant
Arg 498	Gln 498	variant
Tyr 501	Asn 501	variant
His 505	Tyr 505	variant
His 533	-	expression tag
His 534	-	expression tag
His 535	-	expression tag
His 536	-	expression tag
His 537	-	expression tag
His 538	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	93893.5
Non-Polymers*	Number of molecules	7
	Total formula weight	1392.7
All*	Total formula weight	95286.2

*Water molecules are not included.