7ZA1
GPC3-Unc5D octamer structure and role in cell migration
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | E, F, G, H | Netrin receptor UNC5D | polymer | 268 | 30258.0 | 4 | UniProt (F1LW30) Pfam (PF07679) Pfam (PF00090) In PDB | Rattus norvegicus (Norway rat) | Protein unc-5 homolog D |
2 | A, C, D, B | Glypican-3 | polymer | 464 | 53383.7 | 4 | UniProt (P51654) Pfam (PF01153) In PDB | Homo sapiens (human) | GTR2-2,Intestinal protein OCI-5,MXR7 |
3 | I | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 1 | In PDB GlyTouCan (G42666HT) | |||
4 | J, K, M, N | alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 748.7 | 4 | In PDB GlyTouCan (G81315DD) | |||
5 | A, C, D, B, E... | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 12 | Chemie (NAG) | |||
6 | E, F, H | alpha-D-mannopyranose | non-polymer | 180.2 | 6 | Chemie (MAN) |
Sequence modifications
E, F, G, H: 46 - 307 (UniProt: F1LW30)
A, C, D, B: 32 - 483 (UniProt: P51654)
PDB | External Database | Details |
---|---|---|
His 308 | - | expression tag |
His 309 | - | expression tag |
His 310 | - | expression tag |
His 311 | - | expression tag |
His 312 | - | expression tag |
His 313 | - | expression tag |
PDB | External Database | Details |
---|---|---|
Glu 29 | - | expression tag |
Thr 30 | - | expression tag |
Gly 31 | - | expression tag |
Phe 359 | Ser 359 | variant |
Gly 484 | - | expression tag |
Thr 485 | - | expression tag |
Lys 486 | - | expression tag |
His 487 | - | expression tag |
His 488 | - | expression tag |
His 489 | - | expression tag |
His 490 | - | expression tag |
His 491 | - | expression tag |
His 492 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 8 |
Total formula weight | 334566.6 | |
Branched | Number of molecules | 5 |
Total formula weight | 3419.1 | |
Non-Polymers* | Number of molecules | 18 |
Total formula weight | 3735.4 | |
All* | Total formula weight | 341721.1 |