7Z8F
Composite structure of dynein-dynactin-BICDR on microtubules
This is a non-PDB format compatible entry.
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C, D, E... | ARP1 actin related protein 1 homolog A | polymer | 376 | 42670.7 | 8 | UniProt (F2Z5G5) Pfam (PF00022) In PDB | Sus scrofa (pig) | |
2 | H | Actin, cytoplasmic 1 | polymer | 375 | 41782.7 | 1 | UniProt (Q6QAQ1) Pfam (PF00022) In PDB | Sus scrofa (pig) | Beta-actin |
3 | J | Arp11 | polymer | 417 | 46250.8 | 1 | UniProt (I3LHK5) Pfam (PF00022) In PDB | Sus scrofa (pig) | |
4 | K | Capping protein (Actin filament) muscle Z-line, alpha 1 | polymer | 286 | 33059.8 | 1 | UniProt (A0PFK5) Pfam (PF01267) In PDB | Sus scrofa (pig) | F-actin capping protein alpha 1 subunit,F-actin capping protein subunit alpha 1 |
5 | L | F-actin capping protein beta subunit | polymer | 272 | 30669.8 | 1 | UniProt (A9XFX6) Pfam (PF01115) UniProt (by SIFTS) (A0PFK7) In PDB | Sus scrofa (pig) | F-actin-capping protein subunit beta,F-actin-capping protein subunit beta isoform 1 |
6 | M, N, P, Q | Dynactin subunit 2 | polymer | 405 | 44704.4 | 4 | UniProt (A0A5G2QD80) Pfam (PF04912) In PDB | Sus scrofa (pig) | |
7 | O, R | Dynactin subunit 3 | polymer | 186 | 21192.5 | 2 | UniProt (F1SEC0) Pfam (PF07426) In PDB | Sus scrofa (pig) | Dynactin subunit 3 isoform 1 |
8 | S, T | Dynactin subunit 1 | polymer | 1281 | 142015.5 | 2 | UniProt (A0A8D1D718) Pfam (PF01302) Pfam (PF12455) UniProt (by SIFTS) (A0A287B8J2) In PDB | Sus scrofa (pig) | |
9 | U | Dynactin 6 | polymer | 190 | 20703.9 | 1 | UniProt (D0G6S1) In PDB | Sus scrofa (pig) | |
10 | V | Dynactin subunit 5 | polymer | 182 | 20150.5 | 1 | UniProt (A0A286ZK88) Pfam (PF21711) In PDB | Sus scrofa (pig) | |
11 | W, X, w, x | BICD family-like cargo adapter 1 | polymer | 577 | 65377.0 | 4 | UniProt (A0JNT9) In PDB | Mus musculus (house mouse) | Bicaudal D-related protein 1,BICDR-1,Coiled-coil domain-containing protein 64A |
12 | Y | Dynactin subunit 4 | polymer | 467 | 52920.4 | 1 | UniProt (A0A4X1TB62) Pfam (PF05502) In PDB | Sus scrofa (pig) | Dynactin subunit 4 |
13 | e, f, m, n | Cytoplasmic dynein 1 heavy chain 1 | polymer | 4646 | 533055.1 | 4 | UniProt (Q14204) Pfam (PF08385) Pfam (PF08393) Pfam (PF12774) Pfam (PF17852) Pfam (PF12775) Pfam (PF22597) Pfam (PF12780) Pfam (PF12777) Pfam (PF12781) Pfam (PF03028) Pfam (PF18198) Pfam (PF18199) In PDB | Homo sapiens (human) | Cytoplasmic dynein heavy chain 1,Dynein heavy chain,cytosolic |
14 | g, h, o, p | Cytoplasmic dynein 1 intermediate chain 2 | polymer | 638 | 71546.4 | 4 | UniProt (Q13409) Pfam (PF11540) Pfam (PF00400) In PDB | Homo sapiens (human) | Cytoplasmic dynein intermediate chain 2,Dynein intermediate chain 2,cytosolic,DH IC-2 |
15 | i, j, q, r | Cytoplasmic dynein 1 light intermediate chain 2 | polymer | 492 | 54173.2 | 4 | UniProt (O43237) Pfam (PF05783) In PDB | Homo sapiens (human) | Dynein light intermediate chain 2,cytosolic,LIC-2,LIC53/55 |
16 | k, l, s, t | Dynein light chain roadblock-type 1 | polymer | 96 | 10934.6 | 4 | UniProt (Q9NP97) Pfam (PF03259) In PDB | Homo sapiens (human) | Bithoraxoid-like protein,BLP,Dynein light chain 2A,cytoplasmic,Dynein-associated protein Km23,Roadblock domain-containing protein 1 |
17 | F, G, n, H, I... | ADENOSINE-5'-DIPHOSPHATE | non-polymer | 427.2 | 13 | Chemie (ADP) | |||
18 | E, m, F, G, n... | MAGNESIUM ION | non-polymer | 24.3 | 14 | Chemie (MG) | |||
19 | n, J, e, f, m | ADENOSINE-5'-TRIPHOSPHATE | non-polymer | 507.2 | 5 | Chemie (ATP) | |||
20 | Y | ZINC ION | non-polymer | 65.4 | 3 | Chemie (ZN) | |||
21 | m, n, e, f | PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | non-polymer | 506.2 | 8 | Chemie (ANP) |
Sequence modifications
e, f, m, n: 1 - 4646 (UniProt: Q14204)
PDB | External Database | Details |
---|---|---|
Glu 1567 | Arg 1567 | conflict |
Glu 1610 | Lys 1610 | conflict |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 43 |
Total formula weight | 4032482.4 | |
Non-Polymers* | Number of molecules | 43 |
Total formula weight | 12675.6 | |
All* | Total formula weight | 4045158.0 |