7Z21
BAF A12T bound to the lamin A/C Ig-fold domain
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Barrier-to-autointegration factor, N-terminally processed | polymer | 89 | 9901.2 | 4 | UniProt (O75531) Pfam (PF02961) | Homo sapiens (human) | |
| 2 | E, F (E, F) | Lamin-A/C | polymer | 156 | 17342.1 | 2 | UniProt (P02545) Pfam (PF00932) | Homo sapiens (human) | 70 kDa lamin,Renal carcinoma antigen NY-REN-32 |
| 3 | G, H, I, J (A, B, C, D) | CHLORIDE ION | non-polymer | 35.5 | 4 | Chemie (CL) | |||
| 4 | K, L, M, N, O... (A, B, C, D, E...) | water | water | 18.0 | 696 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 2 - 89 (UniProt: O75531)
| PDB | External Database | Details |
|---|---|---|
| Gly 1 | - | expression tag |
| Thr 12 | Ala 12 | variant |
| Ala 67 | Cys 67 | conflict |
| Ala 77 | Cys 77 | conflict |
| Ala 80 | Cys 80 | conflict |
| Ala 85 | Cys 85 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 74289.1 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 141.8 | |
| All* | Total formula weight | 74430.9 |
