7Z1Z
MVV strand transfer complex (STC) intasome in complex with LEDGF/p75 at 3.5 A resolution
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, B, C, D, E...) | Pol polyprotein | polymer | 281 | 32368.8 | 16 | UniProt (P35956) | Visna/maedi virus EV1 KV1772 | |
| 2 | I, J (R, Q) | PC4 and SFRS1-interacting protein | polymer | 95 | 11076.0 | 2 | UniProt (O75475) Pfam (PF11467) | Homo sapiens (human) | CLL-associated antigen KW-7,Dense fine speckles 70 kDa protein,DFS 70,Lens epithelium-derived growth factor,Transcriptional coactivator p75/p52 |
| 3 | K, V (X, Y) | DNA (5'-D(*GP*CP*TP*GP*CP*GP*AP*GP*AP*TP*CP*CP*GP*CP*TP*CP*CP*GP*GP*TP*G)-3') | polymer | 23 | 7064.5 | 2 | DNA molecule | ||
| 4 | L, W (W, Z) | DNA (37-MER) | polymer | 50 | 15387.9 | 2 | DNA molecule | ||
| 5 | M, X (U, a) | DNA (5'-D(P*TP*TP*GP*AP*TP*TP*AP*GP*GP*GP*TP*G)-3') | polymer | 23 | 7073.6 | 2 | DNA molecule | ||
| 6 | AA, BA, CA, DA, EA... (C, E, F, G, I...) | ZINC ION | non-polymer | 65.4 | 12 | Chemie (ZN) |
Sequence modifications
R, Q: 347 - 435 (UniProt: O75475)
| PDB | External Database | Details |
|---|---|---|
| Leu 436 | - | expression tag |
| Glu 437 | - | expression tag |
| Val 438 | - | expression tag |
| Leu 439 | - | expression tag |
| Phe 440 | - | expression tag |
| Gln 441 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 24 |
| Total formula weight | 599105.1 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 784.9 | |
| All* | Total formula weight | 599890.1 |
