7Z0Q
MHC-II dynamics are maintained in HLA-DR allotypes to ensure catalyzed peptide exchange
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (C) | HLA class II histocompatibility antigen, DR alpha chain | polymer | 192 | 22207.1 | 1 | UniProt (P01903) Pfam (PF00993) Pfam (PF07654) | Homo sapiens (human) | MHC class II antigen DRA |
| 2 | B (D) | HLA-DRB1 protein | polymer | 198 | 22967.7 | 1 | UniProt (O19730) Pfam (PF00969) Pfam (PF07654) UniProt (by SIFTS) (D7RIG5) | Homo sapiens (human) | |
| 3 | C (G) | CLIP peptide | polymer | 17 | 1847.3 | 1 | UniProt (by SIFTS) (P04233) | Homo sapiens | |
| 4 | D, E, F, G, H... (C, D, G) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 9 | Chemie (EDO) | |||
| 5 | M, N, O (C, D, G) | water | water | 18.0 | 125 | Chemie (HOH) |
Sequence modifications
C: 1 - 192 (UniProt: P01903)
| PDB | External Database | Details |
|---|---|---|
| Val 192 | Asn 217 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 47022.0 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 558.6 | |
| All* | Total formula weight | 47580.6 |
