7YZ5

Molecular snapshots of drug release from tubulin: 100 milliseconds (steady state)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Tubulin alpha-1B chain	polymer	451	50204.4	1	UniProt (P81947) Pfam (PF00091) Pfam (PF03953)	Bos taurus (cattle)	Alpha-tubulin ubiquitous,Tubulin K-alpha-1,Tubulin alpha-ubiquitous chain
2	B (B)	Tubulin beta-2B chain	polymer	445	49999.9	1	UniProt (Q6B856) Pfam (PF00091) Pfam (PF03953)	Bos taurus (cattle)
3	C (F)	Designed Ankyrin Repeat Protein (DARPIN) D1	polymer	169	18068.4	1		synthetic construct
4	D (A)	GUANOSINE-5'-TRIPHOSPHATE	non-polymer		523.2	1	Chemie (GTP) PubChem (177679032) PubChem (135400627) PubChem (135487750) PubChem (136088935) PubChem (136803486) PubChem (135398633) PubChem (135544356) PubChem (135547949) PubChem (135600366) PubChem (135749822) PubChem (136005188) PubChem (136073923) PubChem (136240914) PubChem (136664747) PubChem (136772743) PubChem (136772744) PubChem (136803487) PubChem (137286749) PubChem (164715984) PubChem (171699466)
5	E (A)	MAGNESIUM ION	non-polymer		24.3	1	Chemie (MG) PubChem (888)
6	F (A)	CALCIUM ION	non-polymer		40.1	1	Chemie (CA) PubChem (271)
7	G (B)	GUANOSINE-5'-DIPHOSPHATE	non-polymer		443.2	1	Chemie (GDP) PubChem (136073927) PubChem (135398619) PubChem (135402030) PubChem (135431654) PubChem (135566337) PubChem (135760556) PubChem (136026707) PubChem (136053418) PubChem (136663964) PubChem (136664748) PubChem (136759848) PubChem (136759849) PubChem (136759850) PubChem (136836636) PubChem (136847074) PubChem (172898537)
8	H, I, J (A, B, F)	water	water		18.0	150	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	118272.8
Non-Polymers*	Number of molecules	4
	Total formula weight	1030.8
All*	Total formula weight	119303.5

*Water molecules are not included.