7YXW
Structure of the p22phox A200G mutant in complex with p47phox peptide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (D) | Cytochrome b-245 light chain | polymer | 18 | 1927.2 | 1 | UniProt (P13498) | Homo sapiens | Cytochrome b(558) alpha chain,Cytochrome b558 subunit alpha,Neutrophil cytochrome b 22 kDa polypeptide,Superoxide-generating NADPH oxidase light chain subunit,p22 phagocyte B-cytochrome,p22-phox,p22phox |
| 2 | B (A) | Neutrophil cytosol factor 1 | polymer | 131 | 14654.3 | 1 | UniProt (P14598) Pfam (PF00018) | Homo sapiens (human) | NCF-1,47 kDa autosomal chronic granulomatous disease protein,47 kDa neutrophil oxidase factor,NCF-47K,Neutrophil NADPH oxidase factor 1,Nox organizer 2,Nox-organizing protein 2,SH3 and PX domain-containing protein 1A,p47-phox |
Sequence modifications
A: 156 - 285 (UniProt: P14598)
| PDB | External Database | Details |
|---|---|---|
| Gly 155 | - | expression tag |
| Asp 166 | Asn 166 | variant |
| Gly 200 | Ala 200 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 16581.5 | |
| All* | Total formula weight | 16581.5 |
