7YXP
Crystal structure of WT AncGR2-LBD WT bound to dexamethasone and SHP coregulator fragment
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Ancestral Glucocorticoid Receptor2 | polymer | 248 | 28649.4 | 1 | UniProt (A0A1X8XLE9) Pfam (PF00104) | unidentified | |
| 2 | B (B) | SHP NR Box 1 Peptide | polymer | 13 | 1378.6 | 1 | UniProt (by SIFTS) (Q15466) | Homo sapiens | |
| 3 | C, D (A) | DEXAMETHASONE | non-polymer | 392.5 | 2 | Chemie (DEX) | |||
| 4 | E (A) | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL | non-polymer | 122.1 | 1 | Chemie (TRS) |
Sequence modifications
A: 530 - 776 (UniProt: A0A1X8XLE9)
| PDB | External Database | Details |
|---|---|---|
| Phe 529 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 30028.0 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 907.1 | |
| All* | Total formula weight | 30935.0 |
