7YXP
Crystal structure of WT AncGR2-LBD WT bound to dexamethasone and SHP coregulator fragment
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Ancestral Glucocorticoid Receptor2 | polymer | 248 | 28649.4 | 1 | UniProt (A0A1X8XLE9) | unidentified | |
| 2 | B (B) | SHP NR Box 1 Peptide | polymer | 13 | 1378.6 | 1 | UniProt (by SIFTS) (Q15466) | Homo sapiens | |
| 3 | C, D (A) | DEXAMETHASONE | non-polymer | 392.5 | 2 | Chemie (DEX) PubChem (3003) PubChem (5743) PubChem (134645) PubChem (146915) PubChem (451600) PubChem (469455) PubChem (656865) PubChem (1150209) PubChem (1426961) PubChem (5702035) PubChem (6610297) PubChem (6610335) PubChem (6710614) PubChem (9830630) PubChem (9865316) PubChem (11014684) PubChem (12358596) PubChem (12358597) PubChem (12358599) PubChem (12358600) PubChem (12358601) PubChem (12358603) PubChem (14697793) PubChem (16757640) PubChem (21140858) PubChem (24758428) PubChem (24848023) PubChem (40467076) PubChem (40469527) PubChem (40469528) PubChem (40469529) PubChem (40469538) PubChem (40469540) PubChem (176476476) PubChem (176476477) PubChem (176481066) PubChem (176519880) PubChem (176541415) PubChem (46870667) PubChem (18609236) PubChem (40467075) PubChem (45791747) PubChem (51654720) PubChem (68625576) PubChem (176476478) PubChem (3036635) PubChem (9782) PubChem (155299) PubChem (71299643) PubChem (51529018) PubChem (969487) PubChem (51723203) PubChem (51723204) PubChem (53316140) PubChem (92043418) PubChem (92259599) PubChem (5702012) PubChem (6432476) PubChem (6546942) PubChem (6604243) PubChem (6603742) PubChem (56627169) PubChem (124301806) PubChem (57959704) PubChem (57959709) PubChem (59499751) PubChem (59553041) PubChem (60032782) PubChem (60107679) PubChem (60107685) PubChem (60113881) PubChem (60129028) PubChem (66739593) PubChem (67968282) PubChem (68163950) PubChem (68346426) PubChem (69301933) PubChem (70211292) PubChem (70834467) PubChem (70965822) PubChem (71083129) PubChem (73707402) PubChem (73945193) PubChem (73950719) PubChem (90141965) PubChem (92259552) PubChem (117072391) PubChem (123132537) PubChem (124190915) PubChem (124304345) PubChem (124904342) PubChem (124904343) PubChem (124918510) PubChem (124918511) PubChem (129010233) PubChem (133634290) PubChem (133645861) PubChem (134990893) PubChem (135396701) PubChem (137704752) PubChem (139404989) PubChem (140662068) PubChem (145705940) PubChem (146436354) PubChem (152964101) PubChem (162730335) PubChem (163285078) PubChem (163285103) PubChem (164010962) PubChem (175434953) PubChem (176282643) | |||
| 4 | E (A) | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL | non-polymer | 122.1 | 1 | Chemie (TRS) PubChem (3777159) |
Sequence modifications
A: 530 - 776 (UniProt: A0A1X8XLE9)
| PDB | External Database | Details |
|---|---|---|
| Phe 529 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 30028.0 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 907.1 | |
| All* | Total formula weight | 30935.0 |
