7YXC
Crystal structure of WT AncGR2-LBD bound to dexamethasone and SHP coregulator fragment
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Ancestral Glucocorticoid Receptor2 | polymer | 248 | 28649.4 | 1 | UniProt (A0A1X8XLE9) Pfam (PF00104) | unidentified | |
| 2 | B (R) | SHP NR Box 1 Peptide | polymer | 11 | 1204.4 | 1 | UniProt (Q15466) | Homo sapiens (human) | Orphan nuclear receptor SHP,Small heterodimer partner,Nuclear receptor subfamily 0 group B member 2 |
| 3 | C (A) | DEXAMETHASONE | non-polymer | 392.5 | 1 | Chemie (DEX) | |||
| 4 | D (A) | TETRAETHYLENE GLYCOL | non-polymer | 194.2 | 1 | Chemie (PG4) | |||
| 5 | E, F (A) | CARBONATE ION | non-polymer | 60.0 | 2 | Chemie (CO3) | |||
| 6 | G, H (A, R) | water | water | 18.0 | 24 | Chemie (HOH) |
Sequence modifications
A: 530 - 776 (UniProt: A0A1X8XLE9)
| PDB | External Database | Details |
|---|---|---|
| Phe 529 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 29853.8 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 706.7 | |
| All* | Total formula weight | 30560.5 |
