7YX8
Crystal structure of the AM0627 (E326A) inactive mutant in complex with PSGL-1-like bis-T glycopeptide and Zn2+
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Peptidase M60 domain-containing protein | polymer | 441 | 49951.5 | 2 | UniProt (B2UPI7) Pfam (PF17291) Pfam (PF13402) | Akkermansia muciniphila | |
| 2 | C, D (F, H) | PSGL-1-like bis-T glycopeptide | polymer | 10 | 1012.1 | 2 | synthetic construct | ||
| 3 | E, F, G, H (D, C, G, E) | beta-D-galactopyranose-(1-3)-2-acetamido-2-deoxy-alpha-D-galactopyranose | branched | 383.3 | 4 | In PDB GlyTouCan (G00031MO) | |||
| 4 | I, J, K, L, M... (A, B) | GLYCEROL | non-polymer | 92.1 | 10 | Chemie (GOL) | |||
| 5 | Q, T (A, B) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 6 | U, V, W, X (A, B, F, H) | water | water | 18.0 | 767 | Chemie (HOH) |
Sequence modifications
A, B: 71 - 506 (UniProt: B2UPI7)
| PDB | External Database | Details |
|---|---|---|
| Gly -4 | - | expression tag |
| Gly -3 | - | expression tag |
| Gly -2 | - | expression tag |
| Gly -1 | - | expression tag |
| Gly 0 | - | expression tag |
| Ala 326 | Glu 326 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 101927.1 | |
| Branched | Number of molecules | 4 |
| Total formula weight | 1533.4 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 1051.8 | |
| All* | Total formula weight | 104512.3 |
