7YW9
Crystal structure of the triple mutant CmnC-L136Q,S138G,D249Y in complex with alpha-KG
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | CmnC | polymer | 358 | 39120.6 | 2 | UniProt (A6YEH4) Pfam (PF02668) | Saccharothrix mutabilis subsp. capreolus | |
| 2 | C, F (A) | TRIETHYLENE GLYCOL | non-polymer | 150.2 | 2 | Chemie (PGE) | |||
| 3 | D, E (A) | ACETATE ION | non-polymer | 59.0 | 2 | Chemie (ACT) | |||
| 4 | G (A) | D-ARGININE | non-polymer | 175.2 | 1 | Chemie (DAR) | |||
| 5 | H, I (A, B) | water | water | 18.0 | 430 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 338 (UniProt: A6YEH4)
| PDB | External Database | Details |
|---|---|---|
| Met -19 | - | initiating methionine |
| Gly -18 | - | expression tag |
| Ser -17 | - | expression tag |
| Ser -16 | - | expression tag |
| His -15 | - | expression tag |
| His -14 | - | expression tag |
| His -13 | - | expression tag |
| His -12 | - | expression tag |
| His -11 | - | expression tag |
| His -10 | - | expression tag |
| Ser -9 | - | expression tag |
| Ser -8 | - | expression tag |
| Gly -7 | - | expression tag |
| Leu -6 | - | expression tag |
| Val -5 | - | expression tag |
| Pro -4 | - | expression tag |
| Arg -3 | - | expression tag |
| Gly -2 | - | expression tag |
| Ser -1 | - | expression tag |
| His 0 | - | expression tag |
| Gln 136 | Leu 136 | engineered mutation |
| Gly 138 | Ser 138 | engineered mutation |
| Tyr 249 | Asp 249 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 78241.1 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 593.6 | |
| All* | Total formula weight | 78834.8 |
