7YRG
histone methyltransferase
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, E | Histone H3.2 | polymer | 103 | 12046.1 | 2 | UniProt (P84233) Pfam (PF00125) In PDB | Xenopus laevis (African clawed frog) | |
2 | B, F | Histone H4 | polymer | 102 | 11265.2 | 2 | UniProt (P62799) Pfam (PF15511) In PDB | Xenopus laevis (African clawed frog) | |
3 | I, J | DNA (146-MER) | polymer | 146 | 45054.8 | 2 | Homo sapiens | ||
4 | C, G | Histone H2A.Z | polymer | 113 | 12091.1 | 2 | UniProt (P0C0S5) Pfam (PF00125) Pfam (PF16211) In PDB | Homo sapiens (human) | H2A/z |
5 | D, H | Histone H2B 1.1 | polymer | 95 | 10607.2 | 2 | UniProt (P02281) Pfam (PF00125) In PDB | Xenopus laevis (African clawed frog) | H2B1.1 |
6 | K, L | [histone H4]-N-methyl-L-lysine20 N-methyltransferase KMT5B | polymer | 279 | 32214.8 | 2 | UniProt (B7WNX0) Pfam (PF00856) UniProt (by SIFTS) (Q4FZB7) In PDB | Homo sapiens (human) | [histone H4]-lysine20 N-methyltransferase KMT5B |
7 | K, L | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
8 | K, L | S-ADENOSYLMETHIONINE | non-polymer | 398.4 | 2 | Chemie (SAM) |
Sequence modifications
A, E: 33 - 135 (UniProt: P84233)
B, F: 1 - 102 (UniProt: P62799)
D, H: 31 - 125 (UniProt: P02281)
PDB | External Database | Details |
---|---|---|
Glu 34 | Gly 35 | engineered mutation |
Ala 102 | Gly 103 | engineered mutation |
PDB | External Database | Details |
---|---|---|
Ecx 20 | Lys 21 | modified residue |
PDB | External Database | Details |
---|---|---|
Thr 32 | Ser 33 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 12 |
Total formula weight | 246558.5 | |
Non-Polymers* | Number of molecules | 4 |
Total formula weight | 927.7 | |
All* | Total formula weight | 247486.2 |