7YMF

Crystal Structure of DDX3X449_450ET>DP

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	ATP-dependent RNA helicase DDX3X	polymer	303	34187.1	1	UniProt (O00571) Pfam (PF00270)	Homo sapiens (human)
2	B (B)	ATP-dependent RNA helicase DDX3X	polymer	178	20255.7	1	UniProt (O00571) Pfam (PF00271)	Homo sapiens (human)
3	C, D (A, B)	water	water		18.0	189	Chemie (HOH)

Sequence modifications

A: 133 - 414 (UniProt: O00571)

PDB	External Database	Details
Met 112	-	initiating methionine
Gly 113	-	expression tag
Ser 114	-	expression tag
Ser 115	-	expression tag
Asp 116	-	expression tag
His 117	-	expression tag
His 118	-	expression tag
His 119	-	expression tag
His 120	-	expression tag
His 121	-	expression tag
Ser 122	-	expression tag
Ser 123	-	expression tag
Gly 124	-	expression tag
Leu 125	-	expression tag
Val 126	-	expression tag
Pro 127	-	expression tag
Arg 128	-	expression tag
Gly 129	-	expression tag
Ser 130	-	expression tag
His 131	-	expression tag
Met 132	-	expression tag

B: 415 - 584 (UniProt: O00571)

PDB	External Database	Details
Asp 449	Glu 449	engineered mutation
Pro 450	Thr 450	engineered mutation
Leu 585	-	expression tag
Glu 586	-	expression tag
His 587	-	expression tag
His 588	-	expression tag
His 589	-	expression tag
His 590	-	expression tag
His 591	-	expression tag
His 592	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	54442.7
All*	Total formula weight	54442.7

*Water molecules are not included.