7YFO

Structure of GluN1a E698C-GluN2D NMDA receptor in cystines crosslinked state.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C (A, C)	Glutamate receptor ionotropic, NMDA 1	polymer	847	95210.1	2	UniProt (Q05586) Pfam (PF01094) Pfam (PF10613) Pfam (PF00060)	Homo sapiens (human)	GluN1,Glutamate [NMDA] receptor subunit zeta-1,N-methyl-D-aspartate receptor subunit NR1,NMD-R1
2	B, D (B, D)	Glutamate receptor ionotropic, NMDA 2D	polymer	891	97226.4	2	UniProt (O15399) Pfam (PF01094) Pfam (PF10613) Pfam (PF00060)	Homo sapiens (human)	GluN2D,EB11,Glutamate [NMDA] receptor subunit epsilon-4,N-methyl D-aspartate receptor subtype 2D,NMDAR2D,NR2D

Sequence modifications

A, C: 1 - 847 (UniProt: Q05586)

PDB	External Database	Details
Cys 698	Glu 698	engineered mutation

B, D: 1 - 879 (UniProt: O15399)

PDB	External Database	Details
Ala 880	-	expression tag
Ala 881	-	expression tag
Ser 882	-	expression tag
Ala 883	-	expression tag
Trp 884	-	expression tag
Ser 885	-	expression tag
His 886	-	expression tag
Pro 887	-	expression tag
Gln 888	-	expression tag
Phe 889	-	expression tag
Glu 890	-	expression tag
Lys 891	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	384873.0
All*	Total formula weight	384873.0

*Water molecules are not included.