7YFJ

Crystal structure of human WTAP

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Pre-mRNA-splicing regulator WTAP	polymer	122	14389.1	2	UniProt (Q15007) Pfam (PF17098)	Homo sapiens (human)	Female-lethal(2)D homolog,hFL(2)D,WT1-associated protein,Wilms tumor 1-associating protein
2	C (B)	1,2-ETHANEDIOL	non-polymer		62.1	1	Chemie (EDO)
3	D (B)	GLYCEROL	non-polymer		92.1	1	Chemie (GOL)
4	E, F (A, B)	water	water		18.0	84	Chemie (HOH)

Sequence modifications

A, B: 1 - 112 (UniProt: Q15007)

PDB	External Database	Details
Leu 113	-	expression tag
Glu 114	-	expression tag
His 115	-	expression tag
His 116	-	expression tag
His 117	-	expression tag
His 118	-	expression tag
His 119	-	expression tag
His 120	-	expression tag
His 121	-	expression tag
His 122	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	28778.2
Non-Polymers*	Number of molecules	2
	Total formula weight	154.2
All*	Total formula weight	28932.4

*Water molecules are not included.