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7YF6

Crystal structure of HIV-1 protease in complex with macrocyclic peptide

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Proteasepolymer9910830.82UniProt (Q9WFL7)
Pfam (PF00077)
UniProt (by SIFTS) (P12497)
Human immunodeficiency virus 1Retropepsin
2C
(C)
Macrocyclic Peptidepolymer91151.51synthetic construct
3D
(B)
MAGNESIUM IONnon-polymer24.31Chemie (MG)
4E, F, G
(A, B, C)
waterwater18.098Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight22813.0
Non-Polymers*Number of molecules1
Total formula weight24.3
All*Total formula weight22837.3
*Water molecules are not included.

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PDB entries from 2025-06-25

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