7YB9
Aspartyl/Asparaginyl beta-hydroxylase (AspH) oxygenase and TPR domains in complex with L-2-hydroxyglutarate and factor X-derived peptide (39mer-4Ser)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Aspartyl/asparaginyl beta-hydroxylase | polymer | 430 | 49534.5 | 1 | UniProt (Q12797) Pfam (PF13432) Pfam (PF05118) | Homo sapiens (human) | Aspartate beta-hydroxylase,ASP beta-hydroxylase,Peptide-aspartate beta-dioxygenase |
| 2 | B (B) | Coagulation factor X | polymer | 39 | 4190.4 | 1 | UniProt (P00742) Pfam (PF00008) | synthetic construct | Stuart factor,Stuart-Prower factor |
| 3 | C (A) | MANGANESE (II) ION | non-polymer | 54.9 | 1 | Chemie (MN) | |||
| 4 | D (A) | (2S)-2-HYDROXYPENTANEDIOIC ACID | non-polymer | 148.1 | 1 | Chemie (S2G) | |||
| 5 | E, F (A, B) | water | water | 18.0 | 408 | Chemie (HOH) |
Sequence modifications
B: 86 - 124 (UniProt: P00742)
| PDB | External Database | Details |
|---|---|---|
| Ser 90 | Cys 90 | engineered mutation |
| Ser 95 | Cys 95 | engineered mutation |
| Ser 112 | Cys 112 | engineered mutation |
| Ser 121 | Cys 121 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 53724.9 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 203.1 | |
| All* | Total formula weight | 53928.0 |
