7Y9C
Crystal structure of METTL9 in complex with SLC39A5 peptide and SAH
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Protein-L-histidine N-pros-methyltransferase | polymer | 275 | 31554.0 | 2 | UniProt (Q9H1A3) Pfam (PF05219) In PDB | Homo sapiens (human) | DORA reverse strand protein,DREV,DREV1,Methyltransferase-like protein 9,hMETTL9, METTL9 |
2 | C, D | SLC39A5 | polymer | 13 | 1375.4 | 2 | UniProt (by SIFTS) (Q6ZMH5) In PDB | synthetic construct | |
3 | A, B | S-ADENOSYL-L-HOMOCYSTEINE | non-polymer | 384.4 | 2 | Chemie (SAH) | |||
4 | water | water | 18.0 | 394 | Chemie (HOH) |
Sequence modifications
A, B: 46 - 318 (UniProt: Q9H1A3)
PDB | External Database | Details |
---|---|---|
His 44 | - | expression tag |
Met 45 | - | expression tag |
Ala 95 | Leu 95 | engineered mutation |
Ala 96 | Phe 96 | engineered mutation |
Ala 99 | Leu 99 | engineered mutation |
Ala 103 | Phe 103 | engineered mutation |
Ala 107 | Val 107 | engineered mutation |
Ala 111 | Phe 111 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 65858.8 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 768.8 | |
All* | Total formula weight | 66627.6 |