7XW7

TSHR-K1-70 complex

This is a non-PDB format compatible entry.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	K1-70 scFv	polymer	227	24400.2	1		Homo sapiens
2	B (R)	Thyrotropin receptor	polymer	702	79894.7	1	UniProt (P16473) Pfam (PF13306) Pfam (PF00001)	Homo sapiens (human)	Thyroid-stimulating hormone receptor,TSH-R

Sequence modifications

R: 21 - 764 (UniProt: P16473)

PDB	External Database	Details
-	Ala 317	deletion
-	Leu 318	deletion
-	Asn 319	deletion
-	Ser 320	deletion
-	Pro 321	deletion
-	Leu 322	deletion
-	His 323	deletion
-	Gln 324	deletion
-	Glu 325	deletion
-	Tyr 326	deletion
-	Glu 327	deletion
-	Glu 328	deletion
-	Asn 329	deletion
-	Leu 330	deletion
-	Gly 331	deletion
-	Asp 332	deletion
-	Ser 333	deletion
-	Ile 334	deletion
-	Val 335	deletion
-	Gly 336	deletion
-	Tyr 337	deletion
-	Lys 338	deletion
-	Glu 339	deletion
-	Lys 340	deletion
-	Ser 341	deletion
-	Lys 342	deletion
-	Phe 343	deletion
-	Gln 344	deletion
-	Asp 345	deletion
-	Thr 346	deletion
-	His 347	deletion
-	Asn 348	deletion
-	Asn 349	deletion
-	Ala 350	deletion
-	His 351	deletion
-	Tyr 352	deletion
-	Tyr 353	deletion
-	Val 354	deletion
-	Phe 355	deletion
-	Phe 356	deletion
-	Glu 357	deletion
-	Glu 358	deletion
-	Gln 359	deletion
-	Glu 360	deletion
-	Asp 361	deletion
-	Glu 362	deletion
-	Ile 363	deletion
-	Ile 364	deletion
-	Gly 365	deletion
-	Phe 366	deletion
Asn 367	Gly 367	conflict
Lys 368	Gln 368	conflict
Thr 369	Glu 369	conflict
His 765	-	expression tag
His 766	-	expression tag
His 767	-	expression tag
His 768	-	expression tag
His 769	-	expression tag
His 770	-	expression tag
His 771	-	expression tag
His 772	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	104294.9
All*	Total formula weight	104294.9

*Water molecules are not included.