7XUM

Structure of ATP7B C983S/C985S/D1027A mutant with Cu+ in presence of ATOX1

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Copper-transporting ATPase 2	polymer	1507	162033.5	1	UniProt (P35670) Pfam (PF00403) Pfam (PF00122) Pfam (PF00702)	Homo sapiens (human)	Copper pump 2,Wilson disease-associated protein
2	B (A)	COPPER (II) ION	non-polymer		63.5	1	Chemie (CU)

Sequence modifications

A: 1 - 1465 (UniProt: P35670)

PDB	External Database	Details
Ser 983	Cys 983	engineered mutation
Ser 985	Cys 985	engineered mutation
Ala 1027	Asp 1027	engineered mutation
Val 1466	-	expression tag
Asp 1467	-	expression tag
Glu 1468	-	expression tag
Leu 1469	-	expression tag
Thr 1470	-	expression tag
Ser 1471	-	expression tag
Arg 1472	-	expression tag
Gly 1473	-	expression tag
Arg 1474	-	expression tag
Asp 1475	-	expression tag
Tyr 1476	-	expression tag
Lys 1477	-	expression tag
Asp 1478	-	expression tag
Asp 1479	-	expression tag
Asp 1480	-	expression tag
Asp 1481	-	expression tag
Lys 1482	-	expression tag
Trp 1483	-	expression tag
Ser 1484	-	expression tag
His 1485	-	expression tag
Pro 1486	-	expression tag
Gln 1487	-	expression tag
Phe 1488	-	expression tag
Glu 1489	-	expression tag
Lys 1490	-	expression tag
Gly 1491	-	expression tag
Gly 1492	-	expression tag
Gly 1493	-	expression tag
Gly 1494	-	expression tag
Ser 1495	-	expression tag
Gly 1496	-	expression tag
Gly 1497	-	expression tag
Ser 1498	-	expression tag
Ala 1499	-	expression tag
Trp 1500	-	expression tag
Ser 1501	-	expression tag
His 1502	-	expression tag
Pro 1503	-	expression tag
Gln 1504	-	expression tag
Phe 1505	-	expression tag
Glu 1506	-	expression tag
Lys 1507	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	162033.5
Non-Polymers*	Number of molecules	1
	Total formula weight	63.5
All*	Total formula weight	162097.1

*Water molecules are not included.