7XU2
Structure of SARS-CoV-2 Spike Protein with Engineered x3 Disulfide (x3(D427C, V987C) and single Arg S1/S2 cleavage site), Locked-2 Conformation
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, C, B) | Spike glycoprotein | polymer | 1127 | 124727.2 | 3 | UniProt (P0DTC2) Pfam (PF16451) Pfam (PF09408) Pfam (PF19209) Pfam (PF01601) | Severe acute respiratory syndrome coronavirus 2 | S glycoprotein,E2,Peplomer protein |
| 2 | D, E, F, G, H... (D, E, F, G, H...) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 12 | In PDB GlyTouCan (G42666HT) | |||
| 3 | AA, AB, BB, CB, DA... (A, B, C) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 36 | Chemie (NAG) | |||
| 4 | BA, EB, PA (A, B, C) | BILIVERDINE IX ALPHA | non-polymer | 582.6 | 3 | Chemie (BLA) | |||
| 5 | CA, QA, RA (A, C, B) | LINOLEIC ACID | non-polymer | 280.4 | 3 | Chemie (EIC) |
Sequence modifications
A, C, B: 14 - 1140 (UniProt: P0DTC2)
| PDB | External Database | Details |
|---|---|---|
| Glu 10 | - | expression tag |
| Thr 11 | - | expression tag |
| Gly 12 | - | expression tag |
| Thr 13 | - | expression tag |
| Cys 427 | Asp 427 | engineered mutation |
| - | Pro 681 | deletion |
| - | Arg 682 | deletion |
| - | Arg 683 | deletion |
| - | Ala 684 | deletion |
| Cys 987 | Val 987 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 374181.7 | |
| Branched | Number of molecules | 12 |
| Total formula weight | 5092.8 | |
| Non-Polymers* | Number of molecules | 42 |
| Total formula weight | 10552.8 | |
| All* | Total formula weight | 389827.3 |
