7XU2
Structure of SARS-CoV-2 Spike Protein with Engineered x3 Disulfide (x3(D427C, V987C) and single Arg S1/S2 cleavage site), Locked-2 Conformation
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, C, B | Spike glycoprotein | polymer | 1127 | 124727.2 | 3 | UniProt (P0DTC2) Pfam (PF16451) Pfam (PF09408) Pfam (PF19209) Pfam (PF01601) In PDB | Severe acute respiratory syndrome coronavirus 2 | S glycoprotein,E2,Peplomer protein |
2 | D, E, F, G, H... | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 12 | In PDB GlyTouCan (G42666HT) | |||
3 | A, B, C | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 36 | Chemie (NAG) | |||
4 | A, B, C | BILIVERDINE IX ALPHA | non-polymer | 582.6 | 3 | Chemie (BLA) | |||
5 | A, C, B | LINOLEIC ACID | non-polymer | 280.4 | 3 | Chemie (EIC) |
Sequence modifications
A, C, B: 14 - 1140 (UniProt: P0DTC2)
PDB | External Database | Details |
---|---|---|
Glu 10 | - | expression tag |
Thr 11 | - | expression tag |
Gly 12 | - | expression tag |
Thr 13 | - | expression tag |
Cys 427 | Asp 427 | engineered mutation |
- | Pro 681 | deletion |
- | Arg 682 | deletion |
- | Arg 683 | deletion |
- | Ala 684 | deletion |
Cys 987 | Val 987 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 3 |
Total formula weight | 374181.7 | |
Branched | Number of molecules | 12 |
Total formula weight | 5092.8 | |
Non-Polymers* | Number of molecules | 42 |
Total formula weight | 10552.8 | |
All* | Total formula weight | 389827.3 |