7XTP

eIF4E in Complex with a Disulphide-Free Autonomous VH Domain

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Eukaryotic translation initiation factor 4E	polymer	217	25130.2	2	UniProt (P06730) Pfam (PF01652)	Homo sapiens (human)	eIF4E
2	C, D (C, D)	VH-S4ss	polymer	154	16504.3	2		Homo sapiens
3	E, F (A, B)	[[(2R,3S,4R,5R)-5-(6-AMINO-3-METHYL-4-OXO-5H-IMIDAZO[4,5-C]PYRIDIN-1-YL)-3,4-DIHYDROXY-OXOLAN-2-YL]METHOXY-HYDROXY-PHOSPHORYL] PHOSPHONO HYDROGEN PHOSPHATE	non-polymer		537.2	2	Chemie (MGO)
4	G, H, I, J (A, B, C, D)	water	water		18.0	388	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	83269.1
Non-Polymers*	Number of molecules	2
	Total formula weight	1074.5
All*	Total formula weight	84343.5

*Water molecules are not included.