7XQK

The Crystal Structure of CDK3 and CyclinE1 Complex from Biortus.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Glutathione S-transferase class-mu 26 kDa isozyme,Cyclin-dependent kinase 3	polymer	533	61776.5	1	UniProt (P08515) UniProt (Q00526) Pfam (PF02798) Pfam (PF14497) Pfam (PF00069)	Schistosoma japonicum (Blood fluke)	GST 26,Sj26 antigen,SjGST,Cell division protein kinase 3
2	B (B)	G1/S-specific cyclin-E1	polymer	305	35718.3	1	UniProt (P24864) Pfam (PF00134) Pfam (PF02984)	Homo sapiens (human)
3	C, E, F, G, H... (A, B)	SULFATE ION	non-polymer		96.1	11	Chemie (SO4)
4	D, P, Q (A, B)	GLYCEROL	non-polymer		92.1	3	Chemie (GOL)
5	O (B)	2-(N-MORPHOLINO)-ETHANESULFONIC ACID	non-polymer		195.2	1	Chemie (MES)
6	R, S (A, B)	water	water		18.0	428	Chemie (HOH)

Sequence modifications

A: -227 - -10 (UniProt: P08515)

PDB	External Database	Details
Ser -9	-	linker
Asp -8	-	linker
Leu -7	-	linker
Glu -6	-	linker
Val -5	-	linker
Leu -4	-	linker
Phe -3	-	linker
Gln -2	-	linker
Gly -1	-	linker
Pro 0	-	linker

A: 1 - 305 (UniProt: Q00526)
B: 96 - 378 (UniProt: P24864)

PDB	External Database	Details
Met 74	-	initiating methionine
Asp 75	-	expression tag
Tyr 76	-	expression tag
Lys 77	-	expression tag
Asp 78	-	expression tag
Asp 79	-	expression tag
Asp 80	-	expression tag
Asp 81	-	expression tag
Lys 82	-	expression tag
His 83	-	expression tag
His 84	-	expression tag
His 85	-	expression tag
His 86	-	expression tag
His 87	-	expression tag
His 88	-	expression tag
Glu 89	-	expression tag
Asn 90	-	expression tag
Leu 91	-	expression tag
Tyr 92	-	expression tag
Phe 93	-	expression tag
Gln 94	-	expression tag
Gly 95	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	97494.8
Non-Polymers*	Number of molecules	15
	Total formula weight	1528.2
All*	Total formula weight	99023.0

*Water molecules are not included.