7XMN
Structure of SARS-CoV-2 ORF8
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Maltodextrin-binding protein | polymer | 370 | 40236.4 | 1 | UniProt (A0A376KDN7) Pfam (PF01547) UniProt (by SIFTS) (P0AEX9) | Escherichia coli | |
| 2 | B (B) | ORF8 protein | polymer | 106 | 12236.9 | 1 | UniProt (P0DTC8) Pfam (PF12093) | Severe acute respiratory syndrome coronavirus 2 (2019-nCoV SARS-CoV-2) | ORF8,Non-structural protein 8,ns8 |
| 3 | C (C) | alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose | branched | 342.3 | 1 | In PDB GlyTouCan (G07411ON) | |||
| 4 | D (A) | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID | non-polymer | 195.2 | 1 | Chemie (MES) | |||
| 5 | E, F, G, J, K (A, B) | SULFATE ION | non-polymer | 96.1 | 5 | Chemie (SO4) | |||
| 6 | H (B) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 1 | Chemie (NAG) | |||
| 7 | I (B) | NOR-N-OMEGA-HYDROXY-L-ARGININE | non-polymer | 176.2 | 1 | Chemie (NNH) | |||
| 8 | L, M (A, B) | water | water | 18.0 | 86 | Chemie (HOH) |
Sequence modifications
A: 9 - 374 (UniProt: A0A376KDN7)
| PDB | External Database | Details |
|---|---|---|
| Thr 10 | Ile 28 | conflict |
| Ala 90 | Asp 108 | conflict |
| Ala 91 | Lys 109 | conflict |
| Ala 180 | Glu 198 | conflict |
| Ala 181 | Asn 199 | conflict |
| His 223 | Ala 241 | conflict |
| His 227 | Lys 245 | conflict |
| Ala 247 | Lys 265 | conflict |
| Val 320 | Ala 338 | conflict |
| Val 325 | Ile 343 | conflict |
| Ala 370 | Lys 388 | conflict |
| Ala 371 | Asp 389 | conflict |
| Asn 375 | - | expression tag |
| Ala 376 | - | expression tag |
| Ala 377 | - | expression tag |
| Ala 378 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 52473.4 | |
| Branched | Number of molecules | 1 |
| Total formula weight | 342.3 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 1072.9 | |
| All* | Total formula weight | 53888.6 |
