7XKI

Human Cx36/GJD2 (N-terminal deletion BRIL-fused mutant) gap junction channel in soybean lipids (D6 symmetry)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E... (A, B, C, D, E...)	Gap junction delta-2 protein,Soluble cytochrome b562	polymer	343	39288.3	12	UniProt (Q9UKL4) UniProt (P0ABE7) Pfam (PF00029)	Homo sapiens (human)	Connexin-36,Cx36,Gap junction alpha-9 protein,Cytochrome b-562
2	AA, AB, BA, BB, CA... (D, K, E, L, F...)	1,2-DIMYRISTOYL-RAC-GLYCERO-3-PHOSPHOCHOLINE	non-polymer		677.9	48	Chemie (MC3)

Sequence modifications

A, B, C, D, E, F, G, H, I, J, K, L: 16 - 101 (UniProt: Q9UKL4)

PDB	External Database	Details
-	Gly 2	deletion
-	Glu 3	deletion
-	Trp 4	deletion
-	Thr 5	deletion
-	Ile 6	deletion
-	Leu 7	deletion
-	Glu 8	deletion
-	Arg 9	deletion
-	Leu 10	deletion
-	Leu 11	deletion
-	Glu 12	deletion
-	Ala 13	deletion
-	Ala 14	deletion
-	Val 15	deletion
-	Gln 16	deletion

A, B, C, D, E, F, G, H, I, J, K, L: 101 - 105 (UniProt: P0ABE7)

PDB	External Database	Details
Trp 101	Met 29	engineered mutation
Ile 105	His 124	engineered mutation
Leu 105	Arg 128	engineered mutation

A, B, C, D, E, F, G, H, I, J, K, L: 105 - 321 (UniProt: Q9UKL4)

PDB	External Database	Details
Ser 322	-	expression tag
Arg 323	-	expression tag
Asp 324	-	expression tag
Tyr 325	-	expression tag
Lys 326	-	expression tag
Asp 327	-	expression tag
Asp 328	-	expression tag
Asp 329	-	expression tag
Asp 330	-	expression tag
Lys 331	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	12
	Total formula weight	471459.1
Non-Polymers*	Number of molecules	48
	Total formula weight	32540.8
All*	Total formula weight	503999.9

*Water molecules are not included.