7XJO
Crystal structure of human MMP-2 catalytic domain in complex with inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Matrix metalloproteinase-2 | polymer | 168 | 18809.9 | 2 | Pfam (PF00413) UniProt (by SIFTS) (P08253) In PDB | Homo sapiens | |
| 2 | C, D | RYH-KFB-GLU-ASP-DAB-LEU-EME-EOE-NH2 | polymer | 9 | 1066.1 | 2 | synthetic construct | ||
| 3 | A, B | ZINC ION | non-polymer | 65.4 | 4 | Chemie (ZN) | |||
| 4 | A, B | CALCIUM ION | non-polymer | 40.1 | 7 | Chemie (CA) | |||
| 5 | A | 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL | non-polymer | 282.3 | 1 | Chemie (B3P) | |||
| 6 | A, B | CHLORIDE ION | non-polymer | 35.5 | 3 | Chemie (CL) | |||
| 7 | water | water | 18.0 | 242 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 39752.1 | |
| Non-Polymers* | Number of molecules | 15 |
| Total formula weight | 930.9 | |
| All* | Total formula weight | 40682.9 |
