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7XI7

Human dihydrofolate reductase complexed with P39

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Dihydrofolate reductasepolymer18721480.71UniProt (P00374)
Pfam (PF00186)
Homo sapiens (human)
2B
(A)
6-hexyl-5-phenyl-pyrimidine-2,4-diaminenon-polymer270.41Chemie (4RI)
3C, D, E
(A)
SULFATE IONnon-polymer96.13Chemie (SO4)
4F
(A)
waterwater18.0293Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight21480.7
Non-Polymers*Number of molecules4
Total formula weight558.6
All*Total formula weight22039.3
*Water molecules are not included.

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PDB entries from 2026-01-21

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