7XHV

Crystal Structure of the NPAS4-ARNT heterodimer in complex with DNA

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Aryl hydrocarbon receptor nuclear translocator	polymer	279	30942.2	1	UniProt (P53762) Pfam (PF00010) Pfam (PF00989)	Mus musculus (house mouse)	ARNT protein,Dioxin receptor,nuclear translocator,Hypoxia-inducible factor 1-beta,HIF-1-beta,HIF1-beta
2	B (B)	Neuronal PAS domain-containing protein 4	polymer	211	23343.8	1	UniProt (Q8BGD7) Pfam (PF23183)	Mus musculus (house mouse)	Neuronal PAS4,HLH-PAS transcription factor NXF,Limbic-enhanced PAS protein,LE-PAS
3	C (C)	DNA (5'-D(P*GP*GP*AP*GP*GP*TP*CP*GP*TP*GP*AP*GP*TP*GP*AP*T)-3')	polymer	16	5034.3	1		Mus musculus
4	D (D)	DNA (5'-D(P*CP*CP*AP*TP*CP*AP*CP*TP*CP*AP*CP*GP*AP*CP*CP*T)-3')	polymer	16	4763.1	1		Mus musculus

Sequence modifications

B: 1 - 206 (UniProt: Q8BGD7)

PDB	External Database	Details
His 207	-	expression tag
His 208	-	expression tag
His 209	-	expression tag
His 210	-	expression tag
His 211	-	expression tag
His 212	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	64083.4
All*	Total formula weight	64083.4

*Water molecules are not included.