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7XE3

Crystal structure of LSD2 in complex with cis-4-Br-2,5-F2-PCPA (S1024)

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, BLysine-specific histone demethylase 1Bpolymer79389014.62UniProt (Q8NB78)
Pfam (PF07496)
Pfam (PF04433)
Pfam (PF01593)
In PDB
Homo sapiens (human)Flavin-containing amine oxidase domain-containing protein 1,Lysine-specific histone demethylase 2
2A, BZINC IONnon-polymer65.46Chemie (ZN)
3A, BFLAVIN-ADENINE DINUCLEOTIDEnon-polymer785.52Chemie (FAD)
4A, B3-[4-bromanyl-2,5-bis(fluoranyl)phenyl]propanalnon-polymer249.12Chemie (8A2)
5ACITRATE ANIONnon-polymer189.11Chemie (FLC)
6ATETRAETHYLENE GLYCOLnon-polymer194.21Chemie (PG4)
7A, B1,2-ETHANEDIOLnon-polymer62.12Chemie (EDO)
8waterwater18.0212Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight178029.2
Non-Polymers*Number of molecules14
Total formula weight2969.1
All*Total formula weight180998.3
*Water molecules are not included.

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PDB entries from 2024-09-11

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