7XD9

Crystal Structure of Dengue Virus serotype 2 (DENV2) Polymerase Elongation Complex (CTP Form)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, D, G, J, M...	NS5	polymer	647	75110.3	6	UniProt (Q91H74) Pfam (PF00972) Pfam (PF20483) In PDB	Dengue virus 2
2	B, E, H, K, N...	RNA (30-mer)	polymer	30	9621.8	6		synthetic construct
3	C, F, I, L, O...	RNA (9-mer)	polymer	9	2880.8	6		synthetic construct
4	D, P, G, J, A...	MAGNESIUM ION	non-polymer		24.3	12	Chemie (MG)
5	M, D, P, G, J...	ZINC ION	non-polymer		65.4	12	Chemie (ZN)
6	M, D, E, H, J...	GLYCEROL	non-polymer		92.1	12	Chemie (GOL)
7	M, D, P, G, J...	CYTIDINE-5'-TRIPHOSPHATE	non-polymer		483.2	6	Chemie (CTP)
8		water	water		18.0	494	Chemie (HOH)

Sequence modifications

A, D, G, J, M, P: 264 - 900 (UniProt: Q91H74)

PDB	External Database	Details
Gly 901	-	expression tag
Ser 902	-	expression tag
Ser 903	-	expression tag
Ser 904	-	expression tag
His 905	-	expression tag
His 906	-	expression tag
His 907	-	expression tag
His 908	-	expression tag
His 909	-	expression tag
His 910	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	18
	Total formula weight	525677.1
Non-Polymers*	Number of molecules	42
	Total formula weight	5080.6
All*	Total formula weight	530757.7

*Water molecules are not included.