7XBB
Crystal structure of PDE4D catalytic domain complexed with compound 23a
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Isoform 3 of cAMP-specific 3',5'-cyclic phosphodiesterase 4D | polymer | 507 | 57859.5 | 2 | UniProt (Q08499) Pfam (PF18100) Pfam (PF00233) | Homo sapiens (human) | DPDE3,PDE43 |
| 2 | C, F (A, B) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 3 | D, G (A, B) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 4 | E, H (A, B) | (2~{R},4~{S})-6-ethyl-2-[(2~{E})-2-hydroxyiminoethyl]-2,8-dimethyl-4-(2-methylprop-1-enyl)-3,4-dihydropyrano[3,2-c][1,8]naphthyridin-5-one | non-polymer | 369.5 | 2 | Chemie (B6V) | |||
| 5 | I, J (A, B) | water | water | 18.0 | 417 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 115719.0 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 918.3 | |
| All* | Total formula weight | 116637.4 |
