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7X8P

Frizzled 2 CRD in complex with pF7_A5 Fab

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, D
(A, D)
Frizzled-2polymer13215149.22UniProt (Q14332)
Pfam (PF01392)
Homo sapiens (human)Fz-2,hFz2,FzE2
2B, E
(B, E)
Antibody pF7_A5 Fab, Light chainpolymer21222477.92synthetic construct
3C, F
(C, F)
Antibody pF7_A5 Fab, Heavy chainpolymer22923997.92synthetic construct
4G, I
(A, D)
2-acetamido-2-deoxy-beta-D-glucopyranosenon-polymer221.22Chemie (NAG)
5H
(D)
PALMITOLEIC ACIDnon-polymer254.41Chemie (PAM)
6J, K, L, M, N...
(A, B, C, D, E...)
waterwater18.0315Chemie (HOH)
Sequence modifications
A, D: 34 - 159 (UniProt: Q14332)
PDBExternal DatabaseDetails
His 160-expression tag
His 161-expression tag
His 162-expression tag
His 163-expression tag
His 164-expression tag
His 165-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains6
Total formula weight123250.1
Non-Polymers*Number of molecules3
Total formula weight696.8
All*Total formula weight123946.9
*Water molecules are not included.

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PDB entries from 2025-12-03

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