7X8P

Frizzled 2 CRD in complex with pF7_A5 Fab

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, D	Frizzled-2	polymer	132	15149.2	2	UniProt (Q14332) Pfam (PF01392) In PDB	Homo sapiens (human)	Fz-2,hFz2,FzE2
2	B, E	Antibody pF7_A5 Fab, Light chain	polymer	212	22477.9	2		synthetic construct
3	C, F	Antibody pF7_A5 Fab, Heavy chain	polymer	229	23997.9	2		synthetic construct
4	A, D	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	2	Chemie (NAG)
5	D	PALMITOLEIC ACID	non-polymer		254.4	1	Chemie (PAM)
6		water	water		18.0	315	Chemie (HOH)

Sequence modifications

A, D: 34 - 159 (UniProt: Q14332)

PDB	External Database	Details
His 160	-	expression tag
His 161	-	expression tag
His 162	-	expression tag
His 163	-	expression tag
His 164	-	expression tag
His 165	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	123250.1
Non-Polymers*	Number of molecules	3
	Total formula weight	696.8
All*	Total formula weight	123946.9

*Water molecules are not included.