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7X5O

Crystal structure of E. faecium SHMT in complex with Me-THF and PLP-Gly

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Serine hydroxymethyltransferasepolymer41745005.02UniProt (A0A133CK16)
Pfam (PF00464)
UniProt (by SIFTS) (I3U4H4)
Enterococcus faeciumSHMT,Serine methylase
2C, E, F
(A, B)
N-[4-({[(6S)-2-AMINO-4-HYDROXY-5-METHYL-5,6,7,8-TETRAHYDROPTERIDIN-6-YL]METHYL}AMINO)BENZOYL]-L-GLUTAMIC ACIDnon-polymer459.53Chemie (THH)
3D, G
(A, B)
N-GLYCINE-[3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YL-METHANE]non-polymer306.22Chemie (PLG)
4H, I
(A, B)
waterwater18.0197Chemie (HOH)
Sequence modifications
A, B: 2 - 414 (UniProt: A0A133CK16)
PDBExternal DatabaseDetails
Gly -2-expression tag
Pro -1-expression tag
Gly 0-expression tag
Val 1-see sequence details
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight90010.1
Non-Polymers*Number of molecules5
Total formula weight1990.8
All*Total formula weight92000.9
*Water molecules are not included.

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PDB entries from 2025-06-11

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