7X5N
Crystal structure of E. faecium SHMT in complex with (+)-SHIN-1 and PLP-Ser
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Serine hydroxymethyltransferase | polymer | 417 | 45005.0 | 2 | UniProt (A0A133CK16) Pfam (PF00464) UniProt (by SIFTS) (I3U4H4) | Enterococcus faecium | SHMT,Serine methylase |
| 2 | C, E (A, B) | (4R)-6-azanyl-4-[3-(hydroxymethyl)-5-phenyl-phenyl]-3-methyl-4-propan-2-yl-1H-pyrano[2,3-c]pyrazole-5-carbonitrile | non-polymer | 400.5 | 2 | Chemie (5M5) | |||
| 3 | D, F (A, B) | [3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YLMETHYL]-SERINE | non-polymer | 336.2 | 2 | Chemie (PLS) | |||
| 4 | G, H (A, B) | water | water | 18.0 | 535 | Chemie (HOH) |
Sequence modifications
A, B: 2 - 414 (UniProt: A0A133CK16)
| PDB | External Database | Details |
|---|---|---|
| Gly -2 | - | expression tag |
| Pro -1 | - | expression tag |
| Gly 0 | - | expression tag |
| Val 1 | - | see sequence details |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 90010.1 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1473.4 | |
| All* | Total formula weight | 91483.5 |
