7X2U
Structure of a human NHE3-CHP1 complex in the autoinhibited state
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Sodium/hydrogen exchanger 3 | polymer | 626 | 70537.0 | 2 | UniProt (P48764) Pfam (PF00999) | Homo sapiens (human) | Na(+)/H(+) exchanger 3,NHE-3,Solute carrier family 9 member 3 |
| 2 | C, D (C, D) | Calcineurin B homologous protein 1 | polymer | 185 | 21411.9 | 2 | UniProt (Q99653) Pfam (PF00036) | Homo sapiens (human) | Calcineurin B-like protein,Calcium-binding protein CHP,Calcium-binding protein p22,EF-hand calcium-binding domain-containing protein p22 |
| 3 | E, L (A, B) | [(2~{R})-2-hexadecanoyloxy-3-[oxidanyl-[(2~{S},3~{S},5~{R},6~{S})-2,3,4,5,6-pentakis(oxidanyl)cyclohexyl]oxy-phosphoryl]oxy-propyl] hexadecanoate | non-polymer | 811.0 | 2 | Chemie (85R) | |||
| 4 | F, G, H, I, J... (A, B) | (1S)-2-{[{[(2R)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL STEARATE | non-polymer | 751.0 | 10 | Chemie (PGT) |
Sequence modifications
C, D: 11 - 195 (UniProt: Q99653)
| PDB | External Database | Details |
|---|---|---|
| Ile 170 | Ala 170 | conflict |
| Ala 171 | Ile 171 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 183897.9 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 9132.3 | |
| All* | Total formula weight | 193030.2 |
