7X09
Homo sapiens Prolyl-tRNA Synthetase (HsPRS) in Complex with inhibitors L95 and Halofuginone
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Bifunctional glutamate/proline--tRNA ligase | polymer | 505 | 57530.8 | 2 | UniProt (P07814) Pfam (PF00587) Pfam (PF03129) Pfam (PF09180) | Homo sapiens (human) | Bifunctional aminoacyl-tRNA synthetase,Cell proliferation-inducing gene 32 protein,Glutamatyl-prolyl-tRNA synthetase |
| 2 | C, J (A, B) | 7-bromo-6-chloro-3-{3-[(2R,3S)-3-hydroxypiperidin-2-yl]-2-oxopropyl}quinazolin-4(3H)-one | non-polymer | 414.7 | 2 | Chemie (HFG) | |||
| 3 | D, K (A, B) | ~{N}-[4-[(3~{S})-3-cyano-3-cyclopropyl-2-oxidanylidene-pyrrolidin-1-yl]-6-methyl-pyridin-2-yl]-2-phenyl-ethanamide | non-polymer | 374.4 | 2 | Chemie (JE6) | |||
| 4 | E, G, L, N (A, B) | ZINC ION | non-polymer | 65.4 | 4 | Chemie (ZN) | |||
| 5 | F, M (A, B) | BROMIDE ION | non-polymer | 79.9 | 2 | Chemie (BR) | |||
| 6 | H, O, R (A, B) | CALCIUM ION | non-polymer | 40.1 | 3 | Chemie (CA) | |||
| 7 | I (A) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 8 | P, Q (B) | CHLORIDE ION | non-polymer | 35.5 | 2 | Chemie (CL) | |||
| 9 | S, T (A, B) | water | water | 18.0 | 554 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 115061.7 | |
| Non-Polymers* | Number of molecules | 16 |
| Total formula weight | 2282.9 | |
| All* | Total formula weight | 117344.6 |
