7WZC
An open conformation Form2 of switch II for RhoA GDP-bound state
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Transforming protein RhoA | polymer | 185 | 20936.9 | 1 | UniProt (P61586) Pfam (PF00071) In PDB | Homo sapiens (human) | Rho cDNA clone 12,h12 |
| 2 | A | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 3 | A | GUANOSINE-5'-DIPHOSPHATE | non-polymer | 443.2 | 1 | Chemie (GDP) | |||
| 4 | A | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 5 | water | water | 18.0 | 117 | Chemie (HOH) |
Sequence modifications
A: 1 - 181 (UniProt: P61586)
| PDB | External Database | Details |
|---|---|---|
| Tyr -3 | - | expression tag |
| Phe -2 | - | expression tag |
| Gln -1 | - | expression tag |
| Gly 0 | - | expression tag |
| Val 16 | Cys 16 | engineered mutation |
| Ser 20 | Cys 20 | engineered mutation |
| Val 83 | Cys 83 | engineered mutation |
| Thr 159 | Cys 159 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 20936.9 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 559.6 | |
| All* | Total formula weight | 21496.5 |
