7WTB

Cryo-EM structure of human pyruvate carboxylase with acetyl-CoA

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	Pyruvate carboxylase, mitochondrial	polymer	1178	129799.4	4	UniProt (P11498) Pfam (PF00289) Pfam (PF02786) Pfam (PF02785) Pfam (PF00682) Pfam (PF02436) Pfam (PF00364)	Homo sapiens (human)	Pyruvic carboxylase,PCB
2	E, I, K, L (A, B, C, D)	5-(HEXAHYDRO-2-OXO-1H-THIENO[3,4-D]IMIDAZOL-6-YL)PENTANAL	non-polymer		228.3	4	Chemie (BTI)
3	F, J (A, B)	PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER	non-polymer		506.2	2	Chemie (ANP)
4	G, H (A, B)	ACETYL COENZYME *A	non-polymer		809.6	2	Chemie (ACO)

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	519197.4
Non-Polymers*	Number of molecules	8
	Total formula weight	3544.8
All*	Total formula weight	522742.2

*Water molecules are not included.