7WSZ
human glyoxalase I (with C-ter His tag) in glycerol-bound form
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Lactoylglutathione lyase | polymer | 192 | 21874.9 | 2 | UniProt (Q04760) Pfam (PF00903) | Homo sapiens (human) | Aldoketomutase,Glyoxalase I,Glx I,Ketone-aldehyde mutase,Methylglyoxalase,S-D-lactoylglutathione methylglyoxal lyase |
| 2 | C, L (A, B) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 3 | D, E, F, M (A, B) | GLYCEROL | non-polymer | 92.1 | 4 | Chemie (GOL) | |||
| 4 | G, H, N (A, B) | BORIC ACID | non-polymer | 61.8 | 3 | Chemie (BO3) | |||
| 5 | I (A) | IMIDAZOLE | non-polymer | 69.1 | 1 | Chemie (IMD) | |||
| 6 | J, K (A) | BETA-MERCAPTOETHANOL | non-polymer | 78.1 | 2 | Chemie (BME) | |||
| 7 | O, P (A, B) | water | water | 18.0 | 287 | Chemie (HOH) |
Sequence modifications
A, B: 0 - 183 (UniProt: Q04760)
| PDB | External Database | Details |
|---|---|---|
| Leu 184 | - | expression tag |
| Glu 185 | - | expression tag |
| His 186 | - | expression tag |
| His 187 | - | expression tag |
| His 188 | - | expression tag |
| His 189 | - | expression tag |
| His 190 | - | expression tag |
| His 191 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 43749.7 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 910.0 | |
| All* | Total formula weight | 44659.8 |






