7WSI
Cryo-EM structure of human NTCP (wild-type) complexed with YN69202Fab
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Sodium/bile acid cotransporter | polymer | 343 | 38198.9 | 1 | UniProt (Q14973) Pfam (PF01758) In PDB | Homo sapiens (human) | |
2 | H | Fab heavy chain from antibody IgG clone number YN69202 | polymer | 249 | 26574.7 | 1 | Mus musculus | ||
3 | L | Fab light chain from antibody IgG clone number YN69202 | polymer | 219 | 24324.0 | 1 | Mus musculus |
Sequence modifications
A: 1 - 319 (UniProt: Q14973)
PDB | External Database | Details |
---|---|---|
Ile 320 | - | expression tag |
Glu 321 | - | expression tag |
Asn 322 | - | expression tag |
Leu 323 | - | expression tag |
Tyr 324 | - | expression tag |
Phe 325 | - | expression tag |
Gln 326 | - | expression tag |
Gly 327 | - | expression tag |
Asp 328 | - | expression tag |
Tyr 329 | - | expression tag |
Lys 330 | - | expression tag |
Asp 331 | - | expression tag |
Asp 332 | - | expression tag |
Asp 333 | - | expression tag |
Asp 334 | - | expression tag |
Lys 335 | - | expression tag |
His 336 | - | expression tag |
His 337 | - | expression tag |
His 338 | - | expression tag |
His 339 | - | expression tag |
His 340 | - | expression tag |
His 341 | - | expression tag |
His 342 | - | expression tag |
His 343 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 3 |
Total formula weight | 89097.6 | |
All* | Total formula weight | 89097.6 |