7WQT

Cryo-EM structure of VWF D'D3 dimer complexed with D1D2 at 4.3 angstron resolution (VWF tube)

This is a non-PDB format compatible entry.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C, I, K, M... (A, B, E, F, G...)	von Willebrand antigen 2	polymer	741	81427.7	16	UniProt (P04275) Pfam (PF00094) Pfam (PF08742) Pfam (PF01826)	Homo sapiens (human)	von Willebrand antigen II
2	AA, B, BA, CA, D... (a, b, C, c, D...)	von Willebrand factor	polymer	490	54232.8	16	UniProt (P04275) Pfam (PF16164) Pfam (PF00094) Pfam (PF08742) Pfam (PF01826)	Homo sapiens (human)	vWF
3	AB, AD, BD, CB, CC... (D, S, d, L, E...)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	42	Chemie (NAG)
4	AC, BB, BC, CD, DB... (K, D, S, d, L...)	CALCIUM ION	non-polymer		40.1	56	Chemie (CA)

Sequence modifications

a, b, C, c, D, d, e, f, S, T, U, V, W, X, Y, Z: 764 - 1241 (UniProt: P04275)

PDB	External Database	Details
Gly 1242	-	expression tag
Leu 1243	-	expression tag
Val 1244	-	expression tag
Val 1245	-	expression tag
Pro 1246	-	expression tag
Pro 1247	-	expression tag
His 1248	-	expression tag
His 1249	-	expression tag
His 1250	-	expression tag
His 1251	-	expression tag
His 1252	-	expression tag
His 1253	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	32
	Total formula weight	2170568.2
Non-Polymers*	Number of molecules	98
	Total formula weight	11535.1
All*	Total formula weight	2182103.3

*Water molecules are not included.