7WPN
Methionyl-tRNA synthetase from Staphylococcus aureus complexed with a phenylbenzimidazole inhibitor and ATP
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Methionine--tRNA ligase | polymer | 530 | 61104.0 | 1 | UniProt (Q5HII6) Pfam (PF09334) Pfam (PF08264) | Staphylococcus aureus subsp. aureus COL (Staphylococcus aureus COL) | Methionyl-tRNA synthetase,MetRS |
| 2 | B (A) | ADENOSINE-5'-TRIPHOSPHATE | non-polymer | 507.2 | 1 | Chemie (ATP) | |||
| 3 | C (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 1 | Chemie (EDO) | |||
| 4 | D (A) | (phenylmethyl) N-[(2R)-2-[2-(4-bromanyl-3-oxidanyl-phenyl)-5-(methylcarbamoyl)benzimidazol-1-yl]-2-(3,4-dimethoxyphenyl)ethyl]carbamate | non-polymer | 659.5 | 1 | Chemie (29I) | |||
| 5 | E (A) | ACETIC ACID | non-polymer | 60.1 | 1 | Chemie (ACY) | |||
| 6 | F (A) | water | water | 18.0 | 28 | Chemie (HOH) |
Sequence modifications
A: 2 - 520 (UniProt: Q5HII6)
| PDB | External Database | Details |
|---|---|---|
| Met -9 | - | initiating methionine |
| Gly -8 | - | expression tag |
| Ser -7 | - | expression tag |
| Ser -6 | - | expression tag |
| His -5 | - | expression tag |
| His -4 | - | expression tag |
| His -3 | - | expression tag |
| His -2 | - | expression tag |
| His -1 | - | expression tag |
| His 0 | - | expression tag |
| Ser 1 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 61104.0 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1288.8 | |
| All* | Total formula weight | 62392.8 |
