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SummaryStructural detailsExperimental detailsFunctional detailsSequence NeighborHistoryDownloads

7WLD

Cryo-EM structure of the human glycosylphosphatidylinositol transamidase complex at 2.53 Angstrom resolution

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(G)		Glycosylphosphatidylinositol anchor attachment 1 proteinpolymer88696990.41UniProt (O43292)
Pfam (PF04114)		Homo sapiens (human)GPI anchor attachment protein 1,GAA1 protein homolog,hGAA1
2B
(K)		GPI-anchor transamidasepolymer64773443.11UniProt (Q92643)
Pfam (PF01650)		Homo sapiens (human)GPI transamidase,GPI8 homolog,hGPI8,Phosphatidylinositol-glycan biosynthesis class K protein,PIG-K
3C
(S)		GPI transamidase component PIG-Spolymer81690421.11UniProt (Q96S52)
Pfam (PF10510)		Homo sapiens (human)Phosphatidylinositol-glycan biosynthesis class S protein
4D
(T)		GPI transamidase component PIG-Tpolymer83194207.31UniProt (Q969N2)
Pfam (PF04113)		Homo sapiens (human)Phosphatidylinositol-glycan biosynthesis class T protein
5E
(U)		Phosphatidylinositol glycan anchor biosynthesis class U proteinpolymer71280691.51UniProt (Q9H490)
Pfam (PF06728)		Homo sapiens (human)Cell division cycle protein 91-like 1,Protein CDC91-like 1,GPI transamidase component PIG-U
6F
(A)		2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranosebranched424.41In PDB
GlyTouCan (G42666HT)
7DA, EA, FA, G, H...
(U, G)		CHOLESTEROL HEMISUCCINATEnon-polymer486.79Chemie (Y01)
8I
(G)		Digitoninnon-polymer1229.31Chemie (AJP)
9J, K
(G)		(4S,7R)-7-[(hexadecanoyloxy)methyl]-4-hydroxy-N,N,N-trimethyl-4,9-dioxo-3,5,8-trioxa-4lambda~5~-phosphahexacosan-1-aminiumnon-polymer763.12Chemie (BJR)
10L
(G)		1,2-dioleoyl-sn-glycero-3-phosphoethanolaminenon-polymer744.01Chemie (PEE)
11P
(K)		CALCIUM IONnon-polymer40.11Chemie (CA)
12Q
(K)		O-[(R)-{[(2R)-2,3-bis(octadecanoyloxy)propyl]oxy}(hydroxy)phosphoryl]-L-serinenon-polymer792.11Chemie (P5S)
13R, W
(S, T)		2-acetamido-2-deoxy-beta-D-glucopyranosenon-polymer221.22Chemie (NAG)
14AA, BA, S, T, U
(U, S)		CHOLESTEROLnon-polymer386.75Chemie (CLR)
15V
(T)		2-azanylethyl [(2~{S},3~{S},4~{S},5~{S},6~{R})-6-(hydroxymethyl)-2,4,5-tris(oxidanyl)oxan-3-yl] hydrogen phosphatenon-polymer303.21Chemie (05E)
16X
(T)		2-amino-2-deoxy-alpha-D-glucopyranosenon-polymer179.21Chemie (PA1)
17Y
(U)		CARDIOLIPINnon-polymer1464.01Chemie (CDL)
18CA
(U)		[(2R)-1-[2-azanylethoxy(oxidanyl)phosphoryl]oxy-3-hexadecanoyloxy-propan-2-yl] octadecanoatenon-polymer720.01Chemie (DKB)
19GA
(U)		[(2~{R})-1-hexadecanoyloxy-3-[[(1~{S},2~{R},3~{R},4~{S},5~{S},6~{R})-2-hexadecanoyloxy-3,4,5,6-tetrakis(oxidanyl)cyclohexyl]oxy-oxidanyl-phosphoryl]oxy-propan-2-yl] (9~{Z},11~{Z})-octadeca-9,11-dienoatenon-polymer1073.51Chemie (06O)
Sequence modifications
G: 2 - 621 (UniProt: O43292)
PDBExternal DatabaseDetails
Met -1-initiating methionine
Gly 0-expression tag
Ser 1-expression tag
Gly 622-expression tag
Thr 623-expression tag
Leu 624-expression tag
Glu 625-expression tag
Val 626-expression tag
Leu 627-expression tag
Phe 628-expression tag
Gln 629-expression tag
Gly 630-expression tag
Pro 631-expression tag
Gly 632-expression tag
Gly 633-expression tag
Ser 634-expression tag
Gly 635-expression tag
Gly 636-expression tag
Ser 637-expression tag
Ala 638-expression tag
Ser 639-expression tag
Val 640-expression tag
Ile 641-expression tag
Lys 642-expression tag
Pro 643-expression tag
Glu 644-expression tag
Met 645-expression tag
Lys 646-expression tag
Ile 647-expression tag
Lys 648-expression tag
Leu 649-expression tag
Arg 650-expression tag
Met 651-expression tag
Glu 652-expression tag
Gly 653-expression tag
Ala 654-expression tag
Val 655-expression tag
Asn 656-expression tag
Gly 657-expression tag
His 658-expression tag
Lys 659-expression tag
Phe 660-expression tag
Val 661-expression tag
Ile 662-expression tag
Glu 663-expression tag
Gly 664-expression tag
Glu 665-expression tag
Gly 666-expression tag
Ile 667-expression tag
Gly 668-expression tag
Lys 669-expression tag
Pro 670-expression tag
Tyr 671-expression tag
Glu 672-expression tag
Gly 673-expression tag
Thr 674-expression tag
Gln 675-expression tag
Thr 676-expression tag
Leu 677-expression tag
Asp 678-expression tag
Leu 679-expression tag
Thr 680-expression tag
Val 681-expression tag
Glu 682-expression tag
Glu 683-expression tag
Gly 684-expression tag
Ala 685-expression tag
Pro 686-expression tag
Leu 687-expression tag
Pro 688-expression tag
Phe 689-expression tag
Ser 690-expression tag
Tyr 691-expression tag
Asp 692-expression tag
Ile 693-expression tag
Leu 694-expression tag
Thr 695-expression tag
Pro 696-expression tag
Ala 697-expression tag
Phe 698-expression tag
Gln 699-expression tag
Tyr 700-expression tag
Gly 701-expression tag
Asn 702-expression tag
Arg 703-expression tag
Ala 704-expression tag
Phe 705-expression tag
Thr 706-expression tag
Lys 707-expression tag
Tyr 708-expression tag
Pro 709-expression tag
Glu 710-expression tag
Asp 711-expression tag
Ile 712-expression tag
Pro 713-expression tag
Asp 714-expression tag
Tyr 715-expression tag
Phe 716-expression tag
Lys 717-expression tag
Gln 718-expression tag
Ala 719-expression tag
Phe 720-expression tag
Pro 721-expression tag
Glu 722-expression tag
Gly 723-expression tag
Tyr 724-expression tag
Ser 725-expression tag
Trp 726-expression tag
Glu 727-expression tag
Arg 728-expression tag
Ser 729-expression tag
Met 730-expression tag
Thr 731-expression tag
Tyr 732-expression tag
Glu 733-expression tag
Asp 734-expression tag
Gln 735-expression tag
Gly 736-expression tag
Ile 737-expression tag
Cys 738-expression tag
Ile 739-expression tag
Ala 740-expression tag
Thr 741-expression tag
Ser 742-expression tag
Asp 743-expression tag
Ile 744-expression tag
Thr 745-expression tag
Met 746-expression tag
Glu 747-expression tag
Gly 748-expression tag
Asp 749-expression tag
Cys 750-expression tag
Phe 751-expression tag
Phe 752-expression tag
Tyr 753-expression tag
Glu 754-expression tag
Ile 755-expression tag
Arg 756-expression tag
Phe 757-expression tag
Asp 758-expression tag
Gly 759-expression tag
Thr 760-expression tag
Asn 761-expression tag
Phe 762-expression tag
Pro 763-expression tag
Pro 764-expression tag
Asn 765-expression tag
Gly 766-expression tag
Pro 767-expression tag
Val 768-expression tag
Met 769-expression tag
Gln 770-expression tag
Lys 771-expression tag
Lys 772-expression tag
Thr 773-expression tag
Leu 774-expression tag
Lys 775-expression tag
Trp 776-expression tag
Glu 777-expression tag
Pro 778-expression tag
Ser 779-expression tag
Thr 780-expression tag
Glu 781-expression tag
Lys 782-expression tag
Met 783-expression tag
Tyr 784-expression tag
Val 785-expression tag
Glu 786-expression tag
Asp 787-expression tag
Gly 788-expression tag
Val 789-expression tag
Leu 790-expression tag
Lys 791-expression tag
Gly 792-expression tag
Asp 793-expression tag
Val 794-expression tag
Glu 795-expression tag
Met 796-expression tag
Ala 797-expression tag
Leu 798-expression tag
Leu 799-expression tag
Leu 800-expression tag
Glu 801-expression tag
Gly 802-expression tag
Gly 803-expression tag
Gly 804-expression tag
His 805-expression tag
Tyr 806-expression tag
Arg 807-expression tag
Cys 808-expression tag
Asp 809-expression tag
Phe 810-expression tag
Lys 811-expression tag
Thr 812-expression tag
Thr 813-expression tag
Tyr 814-expression tag
Lys 815-expression tag
Ala 816-expression tag
Lys 817-expression tag
Lys 818-expression tag
Asp 819-expression tag
Val 820-expression tag
Arg 821-expression tag
Leu 822-expression tag
Pro 823-expression tag
Asp 824-expression tag
Ala 825-expression tag
His 826-expression tag
Glu 827-expression tag
Val 828-expression tag
Asp 829-expression tag
His 830-expression tag
Arg 831-expression tag
Ile 832-expression tag
Glu 833-expression tag
Ile 834-expression tag
Leu 835-expression tag
Ser 836-expression tag
His 837-expression tag
Asp 838-expression tag
Lys 839-expression tag
Asp 840-expression tag
Tyr 841-expression tag
Asn 842-expression tag
Lys 843-expression tag
Val 844-expression tag
Arg 845-expression tag
Leu 846-expression tag
Tyr 847-expression tag
Glu 848-expression tag
His 849-expression tag
Ala 850-expression tag
Glu 851-expression tag
Ala 852-expression tag
Arg 853-expression tag
Tyr 854-expression tag
Ser 855-expression tag
Gly 856-expression tag
Gly 857-expression tag
Gly 858-expression tag
Ser 859-expression tag
Gly 860-expression tag
Gly 861-expression tag
Gly 862-expression tag
Gly 863-expression tag
Ser 864-expression tag
Gly 865-expression tag
Gly 866-expression tag
Gly 867-expression tag
Gly 868-expression tag
Asp 869-expression tag
Tyr 870-expression tag
Lys 871-expression tag
Asp 872-expression tag
Asp 873-expression tag
Asp 874-expression tag
Asp 875-expression tag
Ala 876-expression tag
Asp 877-expression tag
Tyr 878-expression tag
Lys 879-expression tag
Asp 880-expression tag
Asp 881-expression tag
Asp 882-expression tag
Asp 883-expression tag
Ala 884-expression tag
K: 2 - 395 (UniProt: Q92643)
PDBExternal DatabaseDetails
Met -1-initiating methionine
Gly 0-expression tag
Ser 1-expression tag
Gly 396-expression tag
Thr 397-expression tag
Leu 398-expression tag
Glu 399-expression tag
Val 400-expression tag
Leu 401-expression tag
Phe 402-expression tag
Gln 403-expression tag
Gly 404-expression tag
Pro 405-expression tag
Gly 406-expression tag
Gly 407-expression tag
Ser 408-expression tag
Gly 409-expression tag
Gly 410-expression tag
Ser 411-expression tag
Ala 412-expression tag
Ser 413-expression tag
Val 414-expression tag
Ile 415-expression tag
Lys 416-expression tag
Pro 417-expression tag
Glu 418-expression tag
Met 419-expression tag
Lys 420-expression tag
Ile 421-expression tag
Lys 422-expression tag
Leu 423-expression tag
Arg 424-expression tag
Met 425-expression tag
Glu 426-expression tag
Gly 427-expression tag
Ala 428-expression tag
Val 429-expression tag
Asn 430-expression tag
Gly 431-expression tag
His 432-expression tag
Lys 433-expression tag
Phe 434-expression tag
Val 435-expression tag
Ile 436-expression tag
Glu 437-expression tag
Gly 438-expression tag
Glu 439-expression tag
Gly 440-expression tag
Ile 441-expression tag
Gly 442-expression tag
Lys 443-expression tag
Pro 444-expression tag
Tyr 445-expression tag
Glu 446-expression tag
Gly 447-expression tag
Thr 448-expression tag
Gln 449-expression tag
Thr 450-expression tag
Leu 451-expression tag
Asp 452-expression tag
Leu 453-expression tag
Thr 454-expression tag
Val 455-expression tag
Glu 456-expression tag
Glu 457-expression tag
Gly 458-expression tag
Ala 459-expression tag
Pro 460-expression tag
Leu 461-expression tag
Pro 462-expression tag
Phe 463-expression tag
Ser 464-expression tag
Tyr 465-expression tag
Asp 466-expression tag
Ile 467-expression tag
Leu 468-expression tag
Thr 469-expression tag
Pro 470-expression tag
Ala 471-expression tag
Phe 472-expression tag
Gln 473-expression tag
Tyr 474-expression tag
Gly 475-expression tag
Asn 476-expression tag
Arg 477-expression tag
Ala 478-expression tag
Phe 479-expression tag
Thr 480-expression tag
Lys 481-expression tag
Tyr 482-expression tag
Pro 483-expression tag
Glu 484-expression tag
Asp 485-expression tag
Ile 486-expression tag
Pro 487-expression tag
Asp 488-expression tag
Tyr 489-expression tag
Phe 490-expression tag
Lys 491-expression tag
Gln 492-expression tag
Ala 493-expression tag
Phe 494-expression tag
Pro 495-expression tag
Glu 496-expression tag
Gly 497-expression tag
Tyr 498-expression tag
Ser 499-expression tag
Trp 500-expression tag
Glu 501-expression tag
Arg 502-expression tag
Ser 503-expression tag
Met 504-expression tag
Thr 505-expression tag
Tyr 506-expression tag
Glu 507-expression tag
Asp 508-expression tag
Gln 509-expression tag
Gly 510-expression tag
Ile 511-expression tag
Cys 512-expression tag
Ile 513-expression tag
Ala 514-expression tag
Thr 515-expression tag
Ser 516-expression tag
Asp 517-expression tag
Ile 518-expression tag
Thr 519-expression tag
Met 520-expression tag
Glu 521-expression tag
Gly 522-expression tag
Asp 523-expression tag
Cys 524-expression tag
Phe 525-expression tag
Phe 526-expression tag
Tyr 527-expression tag
Glu 528-expression tag
Ile 529-expression tag
Arg 530-expression tag
Phe 531-expression tag
Asp 532-expression tag
Gly 533-expression tag
Thr 534-expression tag
Asn 535-expression tag
Phe 536-expression tag
Pro 537-expression tag
Pro 538-expression tag
Asn 539-expression tag
Gly 540-expression tag
Pro 541-expression tag
Val 542-expression tag
Met 543-expression tag
Gln 544-expression tag
Lys 545-expression tag
Lys 546-expression tag
Thr 547-expression tag
Leu 548-expression tag
Lys 549-expression tag
Trp 550-expression tag
Glu 551-expression tag
Pro 552-expression tag
Ser 553-expression tag
Thr 554-expression tag
Glu 555-expression tag
Lys 556-expression tag
Met 557-expression tag
Tyr 558-expression tag
Val 559-expression tag
Glu 560-expression tag
Asp 561-expression tag
Gly 562-expression tag
Val 563-expression tag
Leu 564-expression tag
Lys 565-expression tag
Gly 566-expression tag
Asp 567-expression tag
Val 568-expression tag
Glu 569-expression tag
Met 570-expression tag
Ala 571-expression tag
Leu 572-expression tag
Leu 573-expression tag
Leu 574-expression tag
Glu 575-expression tag
Gly 576-expression tag
Gly 577-expression tag
Gly 578-expression tag
His 579-expression tag
Tyr 580-expression tag
Arg 581-expression tag
Cys 582-expression tag
Asp 583-expression tag
Phe 584-expression tag
Lys 585-expression tag
Thr 586-expression tag
Thr 587-expression tag
Tyr 588-expression tag
Lys 589-expression tag
Ala 590-expression tag
Lys 591-expression tag
Lys 592-expression tag
Asp 593-expression tag
Val 594-expression tag
Arg 595-expression tag
Leu 596-expression tag
Pro 597-expression tag
Asp 598-expression tag
Ala 599-expression tag
His 600-expression tag
Glu 601-expression tag
Val 602-expression tag
Asp 603-expression tag
His 604-expression tag
Arg 605-expression tag
Ile 606-expression tag
Glu 607-expression tag
Ile 608-expression tag
Leu 609-expression tag
Ser 610-expression tag
His 611-expression tag
Asp 612-expression tag
Lys 613-expression tag
Asp 614-expression tag
Tyr 615-expression tag
Asn 616-expression tag
Lys 617-expression tag
Val 618-expression tag
Arg 619-expression tag
Leu 620-expression tag
Tyr 621-expression tag
Glu 622-expression tag
His 623-expression tag
Ala 624-expression tag
Glu 625-expression tag
Ala 626-expression tag
Arg 627-expression tag
Tyr 628-expression tag
Ser 629-expression tag
Gly 630-expression tag
Gly 631-expression tag
Gly 632-expression tag
Ser 633-expression tag
Gly 634-expression tag
Gly 635-expression tag
Gly 636-expression tag
Tyr 637-expression tag
Pro 638-expression tag
Tyr 639-expression tag
Asp 640-expression tag
Val 641-expression tag
Pro 642-expression tag
Asp 643-expression tag
Tyr 644-expression tag
Ala 645-expression tag
S: 2 - 555 (UniProt: Q96S52)
PDBExternal DatabaseDetails
Met -1-initiating methionine
Gly 0-expression tag
Ser 1-expression tag
Gly 556-expression tag
Thr 557-expression tag
Leu 558-expression tag
Glu 559-expression tag
Val 560-expression tag
Leu 561-expression tag
Phe 562-expression tag
Gln 563-expression tag
Gly 564-expression tag
Pro 565-expression tag
Gly 566-expression tag
Gly 567-expression tag
Ser 568-expression tag
Gly 569-expression tag
Gly 570-expression tag
Ser 571-expression tag
Ala 572-expression tag
Ser 573-expression tag
Val 574-expression tag
Ile 575-expression tag
Lys 576-expression tag
Pro 577-expression tag
Glu 578-expression tag
Met 579-expression tag
Lys 580-expression tag
Ile 581-expression tag
Lys 582-expression tag
Leu 583-expression tag
Arg 584-expression tag
Met 585-expression tag
Glu 586-expression tag
Gly 587-expression tag
Ala 588-expression tag
Val 589-expression tag
Asn 590-expression tag
Gly 591-expression tag
His 592-expression tag
Lys 593-expression tag
Phe 594-expression tag
Val 595-expression tag
Ile 596-expression tag
Glu 597-expression tag
Gly 598-expression tag
Glu 599-expression tag
Gly 600-expression tag
Ile 601-expression tag
Gly 602-expression tag
Lys 603-expression tag
Pro 604-expression tag
Tyr 605-expression tag
Glu 606-expression tag
Gly 607-expression tag
Thr 608-expression tag
Gln 609-expression tag
Thr 610-expression tag
Leu 611-expression tag
Asp 612-expression tag
Leu 613-expression tag
Thr 614-expression tag
Val 615-expression tag
Glu 616-expression tag
Glu 617-expression tag
Gly 618-expression tag
Ala 619-expression tag
Pro 620-expression tag
Leu 621-expression tag
Pro 622-expression tag
Phe 623-expression tag
Ser 624-expression tag
Tyr 625-expression tag
Asp 626-expression tag
Ile 627-expression tag
Leu 628-expression tag
Thr 629-expression tag
Pro 630-expression tag
Ala 631-expression tag
Phe 632-expression tag
Gln 633-expression tag
Tyr 634-expression tag
Gly 635-expression tag
Asn 636-expression tag
Arg 637-expression tag
Ala 638-expression tag
Phe 639-expression tag
Thr 640-expression tag
Lys 641-expression tag
Tyr 642-expression tag
Pro 643-expression tag
Glu 644-expression tag
Asp 645-expression tag
Ile 646-expression tag
Pro 647-expression tag
Asp 648-expression tag
Tyr 649-expression tag
Phe 650-expression tag
Lys 651-expression tag
Gln 652-expression tag
Ala 653-expression tag
Phe 654-expression tag
Pro 655-expression tag
Glu 656-expression tag
Gly 657-expression tag
Tyr 658-expression tag
Ser 659-expression tag
Trp 660-expression tag
Glu 661-expression tag
Arg 662-expression tag
Ser 663-expression tag
Met 664-expression tag
Thr 665-expression tag
Tyr 666-expression tag
Glu 667-expression tag
Asp 668-expression tag
Gln 669-expression tag
Gly 670-expression tag
Ile 671-expression tag
Cys 672-expression tag
Ile 673-expression tag
Ala 674-expression tag
Thr 675-expression tag
Ser 676-expression tag
Asp 677-expression tag
Ile 678-expression tag
Thr 679-expression tag
Met 680-expression tag
Glu 681-expression tag
Gly 682-expression tag
Asp 683-expression tag
Cys 684-expression tag
Phe 685-expression tag
Phe 686-expression tag
Tyr 687-expression tag
Glu 688-expression tag
Ile 689-expression tag
Arg 690-expression tag
Phe 691-expression tag
Asp 692-expression tag
Gly 693-expression tag
Thr 694-expression tag
Asn 695-expression tag
Phe 696-expression tag
Pro 697-expression tag
Pro 698-expression tag
Asn 699-expression tag
Gly 700-expression tag
Pro 701-expression tag
Val 702-expression tag
Met 703-expression tag
Gln 704-expression tag
Lys 705-expression tag
Lys 706-expression tag
Thr 707-expression tag
Leu 708-expression tag
Lys 709-expression tag
Trp 710-expression tag
Glu 711-expression tag
Pro 712-expression tag
Ser 713-expression tag
Thr 714-expression tag
Glu 715-expression tag
Lys 716-expression tag
Met 717-expression tag
Tyr 718-expression tag
Val 719-expression tag
Glu 720-expression tag
Asp 721-expression tag
Gly 722-expression tag
Val 723-expression tag
Leu 724-expression tag
Lys 725-expression tag
Gly 726-expression tag
Asp 727-expression tag
Val 728-expression tag
Glu 729-expression tag
Met 730-expression tag
Ala 731-expression tag
Leu 732-expression tag
Leu 733-expression tag
Leu 734-expression tag
Glu 735-expression tag
Gly 736-expression tag
Gly 737-expression tag
Gly 738-expression tag
His 739-expression tag
Tyr 740-expression tag
Arg 741-expression tag
Cys 742-expression tag
Asp 743-expression tag
Phe 744-expression tag
Lys 745-expression tag
Thr 746-expression tag
Thr 747-expression tag
Tyr 748-expression tag
Lys 749-expression tag
Ala 750-expression tag
Lys 751-expression tag
Lys 752-expression tag
Asp 753-expression tag
Val 754-expression tag
Arg 755-expression tag
Leu 756-expression tag
Pro 757-expression tag
Asp 758-expression tag
Ala 759-expression tag
His 760-expression tag
Glu 761-expression tag
Val 762-expression tag
Asp 763-expression tag
His 764-expression tag
Arg 765-expression tag
Ile 766-expression tag
Glu 767-expression tag
Ile 768-expression tag
Leu 769-expression tag
Ser 770-expression tag
His 771-expression tag
Asp 772-expression tag
Lys 773-expression tag
Asp 774-expression tag
Tyr 775-expression tag
Asn 776-expression tag
Lys 777-expression tag
Val 778-expression tag
Arg 779-expression tag
Leu 780-expression tag
Tyr 781-expression tag
Glu 782-expression tag
His 783-expression tag
Ala 784-expression tag
Glu 785-expression tag
Ala 786-expression tag
Arg 787-expression tag
Tyr 788-expression tag
Ser 789-expression tag
Gly 790-expression tag
Gly 791-expression tag
Gly 792-expression tag
Ser 793-expression tag
Gly 794-expression tag
Gly 795-expression tag
Gly 796-expression tag
Gly 797-expression tag
Gly 798-expression tag
Gly 799-expression tag
Gly 800-expression tag
Gly 801-expression tag
Gly 802-expression tag
Gly 803-expression tag
Gly 804-expression tag
Glu 805-expression tag
Gln 806-expression tag
Lys 807-expression tag
Leu 808-expression tag
Ile 809-expression tag
Ser 810-expression tag
Glu 811-expression tag
Glu 812-expression tag
Asp 813-expression tag
Leu 814-expression tag
T: 2 - 578 (UniProt: Q969N2)
PDBExternal DatabaseDetails
Met -1-initiating methionine
Gly 0-expression tag
Ser 1-expression tag
Gly 579-expression tag
Thr 580-expression tag
Leu 581-expression tag
Glu 582-expression tag
Val 583-expression tag
Leu 584-expression tag
Phe 585-expression tag
Gln 586-expression tag
Gly 587-expression tag
Pro 588-expression tag
Gly 589-expression tag
Gly 590-expression tag
Ser 591-expression tag
Gly 592-expression tag
Gly 593-expression tag
Ser 594-expression tag
Ala 595-expression tag
Ser 596-expression tag
Val 597-expression tag
Ile 598-expression tag
Lys 599-expression tag
Pro 600-expression tag
Glu 601-expression tag
Met 602-expression tag
Lys 603-expression tag
Ile 604-expression tag
Lys 605-expression tag
Leu 606-expression tag
Arg 607-expression tag
Met 608-expression tag
Glu 609-expression tag
Gly 610-expression tag
Ala 611-expression tag
Val 612-expression tag
Asn 613-expression tag
Gly 614-expression tag
His 615-expression tag
Lys 616-expression tag
Phe 617-expression tag
Val 618-expression tag
Ile 619-expression tag
Glu 620-expression tag
Gly 621-expression tag
Glu 622-expression tag
Gly 623-expression tag
Ile 624-expression tag
Gly 625-expression tag
Lys 626-expression tag
Pro 627-expression tag
Tyr 628-expression tag
Glu 629-expression tag
Gly 630-expression tag
Thr 631-expression tag
Gln 632-expression tag
Thr 633-expression tag
Leu 634-expression tag
Asp 635-expression tag
Leu 636-expression tag
Thr 637-expression tag
Val 638-expression tag
Glu 639-expression tag
Glu 640-expression tag
Gly 641-expression tag
Ala 642-expression tag
Pro 643-expression tag
Leu 644-expression tag
Pro 645-expression tag
Phe 646-expression tag
Ser 647-expression tag
Tyr 648-expression tag
Asp 649-expression tag
Ile 650-expression tag
Leu 651-expression tag
Thr 652-expression tag
Pro 653-expression tag
Ala 654-expression tag
Phe 655-expression tag
Gln 656-expression tag
Tyr 657-expression tag
Gly 658-expression tag
Asn 659-expression tag
Arg 660-expression tag
Ala 661-expression tag
Phe 662-expression tag
Thr 663-expression tag
Lys 664-expression tag
Tyr 665-expression tag
Pro 666-expression tag
Glu 667-expression tag
Asp 668-expression tag
Ile 669-expression tag
Pro 670-expression tag
Asp 671-expression tag
Tyr 672-expression tag
Phe 673-expression tag
Lys 674-expression tag
Gln 675-expression tag
Ala 676-expression tag
Phe 677-expression tag
Pro 678-expression tag
Glu 679-expression tag
Gly 680-expression tag
Tyr 681-expression tag
Ser 682-expression tag
Trp 683-expression tag
Glu 684-expression tag
Arg 685-expression tag
Ser 686-expression tag
Met 687-expression tag
Thr 688-expression tag
Tyr 689-expression tag
Glu 690-expression tag
Asp 691-expression tag
Gln 692-expression tag
Gly 693-expression tag
Ile 694-expression tag
Cys 695-expression tag
Ile 696-expression tag
Ala 697-expression tag
Thr 698-expression tag
Ser 699-expression tag
Asp 700-expression tag
Ile 701-expression tag
Thr 702-expression tag
Met 703-expression tag
Glu 704-expression tag
Gly 705-expression tag
Asp 706-expression tag
Cys 707-expression tag
Phe 708-expression tag
Phe 709-expression tag
Tyr 710-expression tag
Glu 711-expression tag
Ile 712-expression tag
Arg 713-expression tag
Phe 714-expression tag
Asp 715-expression tag
Gly 716-expression tag
Thr 717-expression tag
Asn 718-expression tag
Phe 719-expression tag
Pro 720-expression tag
Pro 721-expression tag
Asn 722-expression tag
Gly 723-expression tag
Pro 724-expression tag
Val 725-expression tag
Met 726-expression tag
Gln 727-expression tag
Lys 728-expression tag
Lys 729-expression tag
Thr 730-expression tag
Leu 731-expression tag
Lys 732-expression tag
Trp 733-expression tag
Glu 734-expression tag
Pro 735-expression tag
Ser 736-expression tag
Thr 737-expression tag
Glu 738-expression tag
Lys 739-expression tag
Met 740-expression tag
Tyr 741-expression tag
Val 742-expression tag
Glu 743-expression tag
Asp 744-expression tag
Gly 745-expression tag
Val 746-expression tag
Leu 747-expression tag
Lys 748-expression tag
Gly 749-expression tag
Asp 750-expression tag
Val 751-expression tag
Glu 752-expression tag
Met 753-expression tag
Ala 754-expression tag
Leu 755-expression tag
Leu 756-expression tag
Leu 757-expression tag
Glu 758-expression tag
Gly 759-expression tag
Gly 760-expression tag
Gly 761-expression tag
His 762-expression tag
Tyr 763-expression tag
Arg 764-expression tag
Cys 765-expression tag
Asp 766-expression tag
Phe 767-expression tag
Lys 768-expression tag
Thr 769-expression tag
Thr 770-expression tag
Tyr 771-expression tag
Lys 772-expression tag
Ala 773-expression tag
Lys 774-expression tag
Lys 775-expression tag
Asp 776-expression tag
Val 777-expression tag
Arg 778-expression tag
Leu 779-expression tag
Pro 780-expression tag
Asp 781-expression tag
Ala 782-expression tag
His 783-expression tag
Glu 784-expression tag
Val 785-expression tag
Asp 786-expression tag
His 787-expression tag
Arg 788-expression tag
Ile 789-expression tag
Glu 790-expression tag
Ile 791-expression tag
Leu 792-expression tag
Ser 793-expression tag
His 794-expression tag
Asp 795-expression tag
Lys 796-expression tag
Asp 797-expression tag
Tyr 798-expression tag
Asn 799-expression tag
Lys 800-expression tag
Val 801-expression tag
Arg 802-expression tag
Leu 803-expression tag
Tyr 804-expression tag
Glu 805-expression tag
His 806-expression tag
Ala 807-expression tag
Glu 808-expression tag
Ala 809-expression tag
Arg 810-expression tag
Tyr 811-expression tag
Ser 812-expression tag
Gly 813-expression tag
Gly 814-expression tag
Gly 815-expression tag
Ser 816-expression tag
Gly 817-expression tag
Gly 818-expression tag
Gly 819-expression tag
His 820-expression tag
His 821-expression tag
His 822-expression tag
His 823-expression tag
His 824-expression tag
His 825-expression tag
His 826-expression tag
His 827-expression tag
His 828-expression tag
His 829-expression tag
U: 2 - 435 (UniProt: Q9H490)
PDBExternal DatabaseDetails
Met -1-initiating methionine
Gly 0-expression tag
Ser 1-expression tag
Gly 436-expression tag
Thr 437-expression tag
Leu 438-expression tag
Glu 439-expression tag
Val 440-expression tag
Leu 441-expression tag
Phe 442-expression tag
Gln 443-expression tag
Gly 444-expression tag
Pro 445-expression tag
Gly 446-expression tag
Gly 447-expression tag
Ser 448-expression tag
Gly 449-expression tag
Gly 450-expression tag
Ser 451-expression tag
Ala 452-expression tag
Ser 453-expression tag
Val 454-expression tag
Ile 455-expression tag
Lys 456-expression tag
Pro 457-expression tag
Glu 458-expression tag
Met 459-expression tag
Lys 460-expression tag
Ile 461-expression tag
Lys 462-expression tag
Leu 463-expression tag
Arg 464-expression tag
Met 465-expression tag
Glu 466-expression tag
Gly 467-expression tag
Ala 468-expression tag
Val 469-expression tag
Asn 470-expression tag
Gly 471-expression tag
His 472-expression tag
Lys 473-expression tag
Phe 474-expression tag
Val 475-expression tag
Ile 476-expression tag
Glu 477-expression tag
Gly 478-expression tag
Glu 479-expression tag
Gly 480-expression tag
Ile 481-expression tag
Gly 482-expression tag
Lys 483-expression tag
Pro 484-expression tag
Tyr 485-expression tag
Glu 486-expression tag
Gly 487-expression tag
Thr 488-expression tag
Gln 489-expression tag
Thr 490-expression tag
Leu 491-expression tag
Asp 492-expression tag
Leu 493-expression tag
Thr 494-expression tag
Val 495-expression tag
Glu 496-expression tag
Glu 497-expression tag
Gly 498-expression tag
Ala 499-expression tag
Pro 500-expression tag
Leu 501-expression tag
Pro 502-expression tag
Phe 503-expression tag
Ser 504-expression tag
Tyr 505-expression tag
Asp 506-expression tag
Ile 507-expression tag
Leu 508-expression tag
Thr 509-expression tag
Pro 510-expression tag
Ala 511-expression tag
Phe 512-expression tag
Gln 513-expression tag
Tyr 514-expression tag
Gly 515-expression tag
Asn 516-expression tag
Arg 517-expression tag
Ala 518-expression tag
Phe 519-expression tag
Thr 520-expression tag
Lys 521-expression tag
Tyr 522-expression tag
Pro 523-expression tag
Glu 524-expression tag
Asp 525-expression tag
Ile 526-expression tag
Pro 527-expression tag
Asp 528-expression tag
Tyr 529-expression tag
Phe 530-expression tag
Lys 531-expression tag
Gln 532-expression tag
Ala 533-expression tag
Phe 534-expression tag
Pro 535-expression tag
Glu 536-expression tag
Gly 537-expression tag
Tyr 538-expression tag
Ser 539-expression tag
Trp 540-expression tag
Glu 541-expression tag
Arg 542-expression tag
Ser 543-expression tag
Met 544-expression tag
Thr 545-expression tag
Tyr 546-expression tag
Glu 547-expression tag
Asp 548-expression tag
Gln 549-expression tag
Gly 550-expression tag
Ile 551-expression tag
Cys 552-expression tag
Ile 553-expression tag
Ala 554-expression tag
Thr 555-expression tag
Ser 556-expression tag
Asp 557-expression tag
Ile 558-expression tag
Thr 559-expression tag
Met 560-expression tag
Glu 561-expression tag
Gly 562-expression tag
Asp 563-expression tag
Cys 564-expression tag
Phe 565-expression tag
Phe 566-expression tag
Tyr 567-expression tag
Glu 568-expression tag
Ile 569-expression tag
Arg 570-expression tag
Phe 571-expression tag
Asp 572-expression tag
Gly 573-expression tag
Thr 574-expression tag
Asn 575-expression tag
Phe 576-expression tag
Pro 577-expression tag
Pro 578-expression tag
Asn 579-expression tag
Gly 580-expression tag
Pro 581-expression tag
Val 582-expression tag
Met 583-expression tag
Gln 584-expression tag
Lys 585-expression tag
Lys 586-expression tag
Thr 587-expression tag
Leu 588-expression tag
Lys 589-expression tag
Trp 590-expression tag
Glu 591-expression tag
Pro 592-expression tag
Ser 593-expression tag
Thr 594-expression tag
Glu 595-expression tag
Lys 596-expression tag
Met 597-expression tag
Tyr 598-expression tag
Val 599-expression tag
Glu 600-expression tag
Asp 601-expression tag
Gly 602-expression tag
Val 603-expression tag
Leu 604-expression tag
Lys 605-expression tag
Gly 606-expression tag
Asp 607-expression tag
Val 608-expression tag
Glu 609-expression tag
Met 610-expression tag
Ala 611-expression tag
Leu 612-expression tag
Leu 613-expression tag
Leu 614-expression tag
Glu 615-expression tag
Gly 616-expression tag
Gly 617-expression tag
Gly 618-expression tag
His 619-expression tag
Tyr 620-expression tag
Arg 621-expression tag
Cys 622-expression tag
Asp 623-expression tag
Phe 624-expression tag
Lys 625-expression tag
Thr 626-expression tag
Thr 627-expression tag
Tyr 628-expression tag
Lys 629-expression tag
Ala 630-expression tag
Lys 631-expression tag
Lys 632-expression tag
Asp 633-expression tag
Val 634-expression tag
Arg 635-expression tag
Leu 636-expression tag
Pro 637-expression tag
Asp 638-expression tag
Ala 639-expression tag
His 640-expression tag
Glu 641-expression tag
Val 642-expression tag
Asp 643-expression tag
His 644-expression tag
Arg 645-expression tag
Ile 646-expression tag
Glu 647-expression tag
Ile 648-expression tag
Leu 649-expression tag
Ser 650-expression tag
His 651-expression tag
Asp 652-expression tag
Lys 653-expression tag
Asp 654-expression tag
Tyr 655-expression tag
Asn 656-expression tag
Lys 657-expression tag
Val 658-expression tag
Arg 659-expression tag
Leu 660-expression tag
Tyr 661-expression tag
Glu 662-expression tag
His 663-expression tag
Ala 664-expression tag
Glu 665-expression tag
Ala 666-expression tag
Arg 667-expression tag
Tyr 668-expression tag
Ser 669-expression tag
Gly 670-expression tag
Gly 671-expression tag
Gly 672-expression tag
Ser 673-expression tag
Gly 674-expression tag
Gly 675-expression tag
Gly 676-expression tag
Lys 677-expression tag
Leu 678-expression tag
Glu 679-expression tag
Phe 680-expression tag
Ser 681-expression tag
Ala 682-expression tag
Trp 683-expression tag
Ser 684-expression tag
His 685-expression tag
Pro 686-expression tag
Gln 687-expression tag
Phe 688-expression tag
Glu 689-expression tag
Lys 690-expression tag
Gly 691-expression tag
Gly 692-expression tag
Gly 693-expression tag
Ser 694-expression tag
Gly 695-expression tag
Gly 696-expression tag
Gly 697-expression tag
Ser 698-expression tag
Gly 699-expression tag
Gly 700-expression tag
Ser 701-expression tag
Ala 702-expression tag
Trp 703-expression tag
Ser 704-expression tag
His 705-expression tag
Pro 706-expression tag
Gln 707-expression tag
Phe 708-expression tag
Glu 709-expression tag
Lys 710-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains5
Total formula weight435753.3
BranchedNumber of molecules1
Total formula weight424.4
Non-Polymers*Number of molecules27
Total formula weight14827.8
All*Total formula weight451005.5
*Water molecules are not included.

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PDB entries from 2025-12-24

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