7WKI
Structure of the ultra-affinity complex between CFH and a nanobody
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Complement factor H | polymer | 192 | 22124.0 | 1 | UniProt (P08603) Pfam (PF00084) | Homo sapiens (human) | H factor 1 |
| 2 | B (B) | Anti-CFH nanobody (VHH) | polymer | 142 | 15036.5 | 1 | Vicugna pacos | ||
| 3 | C, D (A, B) | water | water | 18.0 | 25 | Chemie (HOH) |
Sequence modifications
A: 1046 - 1231 (UniProt: P08603)
| PDB | External Database | Details |
|---|---|---|
| His 1232 | - | expression tag |
| His 1233 | - | expression tag |
| His 1234 | - | expression tag |
| His 1235 | - | expression tag |
| His 1236 | - | expression tag |
| His 1237 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 37160.5 | |
| All* | Total formula weight | 37160.5 |
