7WJQ
Crystal structure of GSDMB in complex with Ipah7.8
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Probable E3 ubiquitin-protein ligase ipaH7.8 | polymer | 242 | 27895.4 | 1 | UniProt (P18014) Pfam (PF12468) | Shigella flexneri | Probable RING-type E3 ubiquitin transferase ipaH7.8 |
| 2 | B (B) | Isoform 2 of Gasdermin-B | polymer | 389 | 44482.6 | 1 | UniProt (Q8TAX9) Pfam (PF04598) Pfam (PF17708) | Homo sapiens (human) | Gasdermin-like protein |
| 3 | C, D (A, B) | water | water | 18.0 | 21 | Chemie (HOH) |
Sequence modifications
A: 23 - 264 (UniProt: P18014)
B: 1 - 406 (UniProt: Q8TAX9)
| PDB | External Database | Details |
|---|---|---|
| Asp 262 | Met 262 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Ser 238 | Arg 221 | engineered mutation |
| Ala 239 | Lys 222 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 72378.0 | |
| All* | Total formula weight | 72378.0 |
