7WHZ

SARS-CoV-2 spike protein in complex with three human neutralizing antibodies

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Spike protein S1	polymer	195	21873.5	1	UniProt (P0DTC2) Pfam (PF09408) In PDB	Severe acute respiratory syndrome coronavirus 2	S glycoprotein,E2,Peplomer protein
2	B	XMA04 heavy chain variable domain	polymer	124	13517.0	1		Homo sapiens
3	C	XMA01 heavy chain variable domain	polymer	122	13198.6	1		Homo sapiens
4	D	IGL c4029_light_IGKV1-39_IGKJ2	polymer	107	11616.9	1	UniProt (A0A5C2G4I7) Pfam (PF07686) In PDB	Homo sapiens (human)
5	E	IG c934_light_IGKV1-5_IGKJ1	polymer	107	11781.1	1	UniProt (A0A5C2GTV1) Pfam (PF07686) In PDB	Homo sapiens (human)
6	H	XMA09 heavy chain variable domain	polymer	123	13272.7	1		Homo sapiens
7	L	IG c1437_light_IGLV1-40_IGLJ1	polymer	110	11374.4	1	UniProt (A0A5C2GVU3) Pfam (PF07686) In PDB	Homo sapiens (human)
8	A	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	1	Chemie (NAG)

Sequence modifications

D: 1 - 107 (UniProt: A0A5C2G4I7)

PDB	External Database	Details
Asn 31	Ser 31	conflict
Phe 32	Tyr 32	conflict
Ser 97	Thr 97	conflict

E: 1 - 107 (UniProt: A0A5C2GTV1)

PDB	External Database	Details
Val 9	Ser 9	conflict
Ser 10	Thr 10	conflict
Thr 31	Ser 31	conflict
Glu 50	Lys 50	conflict
Phe 91	Tyr 91	conflict
Tyr 94	Ser 94	conflict

L: 1 - 110 (UniProt: A0A5C2GVU3)

PDB	External Database	Details
Ser 31	Ala 31	conflict
Leu 48	Arg 48	conflict
-	Tyr 100	deletion

Contents of the asymmetric unit

Polymers	Number of chains	7
	Total formula weight	96634.1
Non-Polymers*	Number of molecules	1
	Total formula weight	221.2
All*	Total formula weight	96855.4

*Water molecules are not included.