7WF4
Composite map of human Kv1.3 channel in dalazatide-bound state with beta subunits
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, J, K, L (D, B, F, H) | Potassium voltage-gated channel subfamily A member 3 | polymer | 283 | 31460.5 | 4 | UniProt (P22001) Pfam (PF00520) Pfam (PF07885) | Homo sapiens (human) | HGK5,HLK3,HPCN3,Voltage-gated K(+) channel HuKIII,Voltage-gated potassium channel subunit Kv1.3 |
2 | B, C, E, I (G, I, M, o) | Voltage-gated potassium channel subunit beta-2 | polymer | 328 | 36704.3 | 4 | UniProt (Q13303) Pfam (PF00248) | Homo sapiens (human) | K(+) channel subunit beta-2,Kv-beta-2,hKvbeta2 |
3 | D, F, G, H (J, N, O, P) | Potassium voltage-gated channel subfamily A member 3 | polymer | 106 | 12777.5 | 4 | UniProt (P22001) Pfam (PF02214) | Homo sapiens (human) | HGK5,HLK3,HPCN3,Voltage-gated K(+) channel HuKIII,Voltage-gated potassium channel subunit Kv1.3 |
4 | M, N, O, P (G, I, M, o) | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | non-polymer | 743.4 | 4 | Chemie (NAP) | |||
5 | Q, R, S (B) | POTASSIUM ION | non-polymer | 39.1 | 3 | Chemie (K) | |||
6 | AA, T, U, V, W... (H, D, G, I, M...) | water | water | 18.0 | 100 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 12 |
Total formula weight | 323768.8 | |
Non-Polymers* | Number of molecules | 7 |
Total formula weight | 3090.9 | |
All* | Total formula weight | 326859.7 |